AutismKB 2.0

Annotation Detail for CR1


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Basic Information Top
Gene Symbol:CR1 ( C3BR,C4BR,CD35,KN )
Gene Full Name: complement component (3b/4b) receptor 1 (Knops blood group)
Band: 1q32.2
Quick LinksEntrez ID:1378; OMIM: 120620; Uniprot ID:CR1_HUMAN; ENSEMBL ID: ENSG00000203710; HGNC ID: 2334
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult13 / 19391216
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma3 / 7175541
non-neoplasia0 / 972500 
normal25 / 33603077
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine1 / 2344724
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph1 / 4427022
lymph node15 / 91610163
mammary gland0 / 1532710 
mouth1 / 6705214
muscle0 / 1077150 
nerve1 / 1576863
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217552_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.8
Adipocyte11
AdrenalCortex14.6
Adrenalgland10.25
Amygdala11
Appendix18.4
AtrioventricularNode16.85
BDCA4+_DentriticCells11.05
Bonemarrow16.6
BronchialEpithelialCells10.95
CD105+_Endothelial12.3
CD14+_Monocytes21.5
CD19+_BCells(neg._sel.)15.9
CD33+_Myeloid47.2
CD34+14.25
CD4+_Tcells8.4
CD56+_NKCells12.55
CD71+_EarlyErythroid13.3
CD8+_Tcells9.85
CardiacMyocytes21.7
Caudatenucleus9.85
Cerebellum9.25
CerebellumPeduncles16.8
CiliaryGanglion16.75
CingulateCortex14.35
Colorectaladenocarcinoma10.9
DorsalRootGanglion15.75
FetalThyroid14.1
Fetalbrain10.7
Fetalliver10.3
Fetallung8.65
GlobusPallidus11.6
Heart21.6
Hypothalamus11.3
Kidney12
Leukemia_chronicMyelogenousK-56210.15
Leukemia_promyelocytic-HL-6010.15
Leukemialymphoblastic(MOLT-4)7.9
Liver30.6
Lung12.4
Lymphnode17.65
Lymphoma_burkitts(Daudi)15.3
Lymphoma_burkitts(Raji)18.65
MedullaOblongata9.9
OccipitalLobe9.9
OlfactoryBulb8.5
Ovary11
Pancreas9.8
PancreaticIslet12.4
ParietalLobe13
Pituitary13.5
Placenta11.15
Pons11.65
PrefrontalCortex13.4
Prostate13
Salivarygland10.4
SkeletalMuscle18.3
Skin20.6
SmoothMuscle13
Spinalcord12.15
SubthalamicNucleus11.15
SuperiorCervicalGanglion20.65
TemporalLobe11.05
Testis9.55
TestisGermCell7.25
TestisIntersitial11.15
TestisLeydigCell11.9
TestisSeminiferousTubule9.8
Thalamus12
Thymus8.3
Thyroid13.75
Tongue13.9
Tonsil13.5
Trachea9.4
TrigeminalGanglion25.8
Uterus8.85
UterusCorpus15.6
WholeBlood95.5
Wholebrain9.2
colon11.15
pineal_day12.5
pineal_night12.44
retina13.85
small_intestine10.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P397671
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.17 ± 1.01
Basal Forebrain1.92 ± 0.53
Basal Part of Pons1.47 ± 0.4
Cerebellar Cortex1.6 ± 0.59
Cerebellar Nuclei2.14 ± 0.68
Claustrum2.59 ± 0.86
Epithalamus1.62 ± 0.87
Frontal Lobe1.77 ± 0.72
Globus Pallidus2.71 ± 0.54
Hypothalamus2.06 ± 0.97
Insula1.73 ± 0.65
Limbic Lobe1.83 ± 0.68
Mesencephalon2 ± 0.7
Myelencephalon1.93 ± 0.72
Occipital Lobe1.83 ± 0.7
Parietal Lobe1.83 ± 0.9
Pontine Tegmentum1.93 ± 0.77
Striatum1.97 ± 0.61
Subthalamus1.9 ± 0.67
Temporal Lobe1.84 ± 0.74
Thalamus1.87 ± 0.67
White Matter4.63 ± 0.36
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00034677 13 432 444 HTGKPLEVFPFGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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