AutismKB 2.0

Annotation Detail for CR2


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Basic Information Top
Gene Symbol:CR2 ( C3DR,CD21,SLEB9 )
Gene Full Name: complement component (3d/Epstein Barr virus) receptor 2
Band: 1q32.2
Quick LinksEntrez ID:1380; OMIM: 120650; Uniprot ID:CR2_HUMAN; ENSEMBL ID: ENSG00000117322; HGNC ID: 2336
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult11 / 19391215
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma10 / 71755139
non-neoplasia2 / 9725020
normal87 / 336030725
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain1 / 11009890 
cervix0 / 481710 
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine7 / 23447229
kidney11 / 21177751
larynx0 / 241450 
liver1 / 2077434
lung0 / 3369740 
lymph1 / 4427022
lymph node56 / 91610611
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen16 / 53952296
stomach2 / 9661920
testis5 / 33044215
thymus5 / 8113161
thyroid0 / 474730 
tonsil1 / 1699958
trachea2 / 5241338
umbilical cord0 / 136800 
uterus2 / 2328788
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205544_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts442.05
Adipocyte4.1
AdrenalCortex4.3
Adrenalgland3.5
Amygdala4.3
Appendix4.1
AtrioventricularNode3.25
BDCA4+_DentriticCells4.8
Bonemarrow4
BronchialEpithelialCells4.05
CD105+_Endothelial4.15
CD14+_Monocytes4.4
CD19+_BCells(neg._sel.)133.35
CD33+_Myeloid5.35
CD34+5.25
CD4+_Tcells4.55
CD56+_NKCells4.95
CD71+_EarlyErythroid3.85
CD8+_Tcells4.05
CardiacMyocytes5.25
Caudatenucleus3.7
Cerebellum3.35
CerebellumPeduncles4.65
CiliaryGanglion2.9
CingulateCortex4.2
Colorectaladenocarcinoma4.15
DorsalRootGanglion3.15
FetalThyroid4
Fetalbrain4.15
Fetalliver3.55
Fetallung3.5
GlobusPallidus3.05
Heart5.25
Hypothalamus4.55
Kidney6.1
Leukemia_chronicMyelogenousK-5623.75
Leukemia_promyelocytic-HL-60812.4
Leukemialymphoblastic(MOLT-4)4.65
Liver5.4
Lung4.55
Lymphnode381.3
Lymphoma_burkitts(Daudi)43.2
Lymphoma_burkitts(Raji)287.45
MedullaOblongata3.8
OccipitalLobe3.7
OlfactoryBulb3.25
Ovary2.75
Pancreas3.3
PancreaticIslet4.4
ParietalLobe4.35
Pituitary5.45
Placenta4.25
Pons3.9
PrefrontalCortex5.15
Prostate4.8
Salivarygland9.7
SkeletalMuscle4.85
Skin3.15
SmoothMuscle4.6
Spinalcord4.4
SubthalamicNucleus3.75
SuperiorCervicalGanglion5.35
TemporalLobe3.75
Testis3.5
TestisGermCell3.5
TestisIntersitial3.45
TestisLeydigCell4.05
TestisSeminiferousTubule3.55
Thalamus4.2
Thymus7.8
Thyroid5.25
Tongue4.2
Tonsil702.75
Trachea3.45
TrigeminalGanglion4.1
Uterus3.35
UterusCorpus3.8
WholeBlood4.55
Wholebrain3.5
colon4.15
pineal_day5.08
pineal_night5.02
retina4.975
small_intestine4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15796_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.2 ± 1.04
Basal Forebrain1.79 ± 0.28
Basal Part of Pons1.39 ± 0.47
Cerebellar Cortex1.62 ± 0.71
Cerebellar Nuclei2.1 ± 0.63
Claustrum2.51 ± 0.71
Epithalamus1.37 ± 0.68
Frontal Lobe1.53 ± 0.57
Globus Pallidus2.27 ± 0.37
Hypothalamus1.74 ± 0.65
Insula1.53 ± 0.49
Limbic Lobe1.75 ± 0.61
Mesencephalon1.86 ± 0.66
Myelencephalon1.75 ± 0.68
Occipital Lobe1.84 ± 0.8
Parietal Lobe1.64 ± 0.58
Pontine Tegmentum1.78 ± 0.67
Striatum1.85 ± 0.52
Subthalamus1.92 ± 0.49
Temporal Lobe1.69 ± 0.71
Thalamus1.7 ± 0.59
White Matter2.73 ± 0.97
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00024818 13 617 629 EAPYFYNDTVTFK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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