AutismKB 2.0

Annotation Detail for FAM69B


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Basic Information Top
Gene Symbol:FAM69B ( C9orf136,MGC20262,pp6977 )
Gene Full Name: family with sequence similarity 69, member B
Band: 9q34.3
Quick LinksEntrez ID:138311; OMIM: NA; Uniprot ID:FA69B_HUMAN; ENSEMBL ID: ENSG00000165716; HGNC ID: 28290
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus60 / 564012106
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult44 / 193912122
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma19 / 106883177
head and neck tumor0 / 1363020 
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal125 / 336030737
ovarian tumor6 / 7668278
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain38 / 110098934
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye4 / 21105418
heart13 / 89626145
intestine3 / 23447212
kidney13 / 21177761
larynx0 / 241450 
liver2 / 2077439
lung26 / 33697477
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary6 / 10205158
pancreas14 / 21481265
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta13 / 28082546
prostate5 / 18934526
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11972_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.86 ± 0.55
Basal Forebrain3.49 ± 0.68
Basal Part of Pons4.12 ± 0.61
Cerebellar Cortex4.12 ± 0.47
Cerebellar Nuclei4.06 ± 0.86
Claustrum3.78 ± 0.72
Epithalamus3.91 ± 0.33
Frontal Lobe4.11 ± 0.56
Globus Pallidus3.75 ± 0.57
Hypothalamus3.79 ± 0.6
Insula4.06 ± 0.43
Limbic Lobe4 ± 0.55
Mesencephalon3.88 ± 0.56
Myelencephalon3.96 ± 0.59
Occipital Lobe3.73 ± 0.52
Parietal Lobe3.97 ± 0.48
Pontine Tegmentum3.85 ± 0.64
Striatum3.6 ± 0.58
Subthalamus4.18 ± 0.26
Temporal Lobe4.04 ± 0.59
Thalamus4.05 ± 0.51
White Matter2.16 ± 0.49
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
B230317C12RikCBCerebellum23.29
99.2
B230317C12RikCTXCerebral cortex51.4
43.97
B230317C12RikHIPHippocampal region33.58
45.19
B230317C12RikHPFHippocampal formation39.8
44.94
B230317C12RikHYHypothalamus21.55
19.82
B230317C12RikLSXLateral septal complex24.43
18.89
B230317C12RikMBMidbrain32.69
35.37
B230317C12RikMYMedulla38.34
55.33
B230317C12RikOLFOlfactory bulb33.58
29.99
B230317C12RikPPons34.73
44.77
B230317C12RikPALPallidum31.41
35.68
B230317C12RikRHPRetrohippocampal region48.75
44.48
B230317C12RiksAMYStriatum-like amygdalar nuclei24.43
20.98
B230317C12RikSTRStriatum15.09
12.67
B230317C12RikSTRdStriatum dorsal region13.33
11.46
B230317C12RikSTRvStriatum ventral region13.57
10.98
B230317C12RikTHThalamus40.99
43.02
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018