AutismKB 2.0

Annotation Detail for PTPDC1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PTPDC1 ( FLJ42922,PTP9Q22 )
Gene Full Name: protein tyrosine phosphatase domain containing 1
Band: 9q22.32
Quick LinksEntrez ID:138639; OMIM: NA; Uniprot ID:PTPC1_HUMAN; ENSEMBL ID: ENSG00000158079; HGNC ID: 30184
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus10 / 56401217
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult24 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia5 / 9725051
normal67 / 336030719
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone3 / 7165541
bone marrow0 / 488010 
brain48 / 110098943
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine1 / 2344724
kidney2 / 2117779
larynx0 / 241450 
liver1 / 2077434
lung3 / 3369748
lymph0 / 442700 
lymph node1 / 9161010
mammary gland2 / 15327113
mouth2 / 6705229
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate1 / 1893455
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach0 / 966190 
testis10 / 33044230
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1489_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.36 ± 0.56
Basal Forebrain7.17 ± 0.35
Basal Part of Pons6.74 ± 0.42
Cerebellar Cortex6.55 ± 0.23
Cerebellar Nuclei7.1 ± 0.35
Claustrum6.52 ± 0.39
Epithalamus6.72 ± 0.36
Frontal Lobe6.61 ± 0.42
Globus Pallidus7.31 ± 0.27
Hypothalamus6.5 ± 0.4
Insula6.47 ± 0.32
Limbic Lobe6.73 ± 0.46
Mesencephalon6.57 ± 0.46
Myelencephalon6.7 ± 0.39
Occipital Lobe6.8 ± 0.41
Parietal Lobe6.67 ± 0.38
Pontine Tegmentum6.82 ± 0.39
Striatum7.59 ± 0.36
Subthalamus7.05 ± 0.18
Temporal Lobe6.64 ± 0.27
Thalamus6.65 ± 0.33
White Matter8.22 ± 0.1
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
AW456874CBCerebellum1.57
2.1
AW456874CTXCerebral cortex1.49
1.38
AW456874HIPHippocampal region3.53
3.24
AW456874HPFHippocampal formation3.8
3.2
AW456874HYHypothalamus0.5
0.55
AW456874LSXLateral septal complex13.28
10.33
AW456874MBMidbrain0.81
1.15
AW456874MYMedulla1.28
1.29
AW456874OLFOlfactory bulb3.25
2.93
AW456874PPons1.09
1.47
AW456874PALPallidum1.1
0.81
AW456874RHPRetrohippocampal region4.41
3.27
AW456874sAMYStriatum-like amygdalar nuclei4.23
3.33
AW456874STRStriatum1.7
1.31
AW456874STRdStriatum dorsal region0.5
0.42
AW456874STRvStriatum ventral region0.52
0.44
AW456874THThalamus2.2
3.06
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018