AutismKB 2.0

Annotation Detail for ZNF358


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Basic Information Top
Gene Symbol:ZNF358 ( FLJ10390,ZFEND )
Gene Full Name: zinc finger protein 358
Band: 19p13.2
Quick LinksEntrez ID:140467; OMIM: NA; Uniprot ID:ZN358_HUMAN; ENSEMBL ID: ENSG00000198816; HGNC ID: 16838
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus10 / 56401217
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult75 / 193912138
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor2 / 3436658
chondrosarcoma6 / 8282372
colorectal tumor2 / 11424617
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor6 / 26384522
glioma9 / 10688384
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal91 / 336030727
ovarian tumor7 / 7668291
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain25 / 110098922
cervix2 / 4817141
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus1 / 2020949
eye11 / 21105452
heart0 / 896260 
intestine8 / 23447234
kidney6 / 21177728
larynx0 / 241450 
liver0 / 2077430 
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle7 / 10771564
nerve0 / 157680 
ovary10 / 10205197
pancreas14 / 21481265
parathyroid1 / 2053948
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta9 / 28082532
prostate7 / 18934536
salivary gland0 / 201550 
skin3 / 21057414
spleen1 / 5395218
stomach3 / 9661931
testis5 / 33044215
thymus3 / 8113136
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219379_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts14.8
Adipocyte19
AdrenalCortex18.6
Adrenalgland12.35
Amygdala20.1
Appendix14.65
AtrioventricularNode16.35
BDCA4+_DentriticCells11.85
Bonemarrow13.45
BronchialEpithelialCells13.95
CD105+_Endothelial13.4
CD14+_Monocytes14
CD19+_BCells(neg._sel.)16.1
CD33+_Myeloid15.55
CD34+21.5
CD4+_Tcells16.5
CD56+_NKCells18.25
CD71+_EarlyErythroid12.8
CD8+_Tcells13.05
CardiacMyocytes13.7
Caudatenucleus16.45
Cerebellum11.6
CerebellumPeduncles23.55
CiliaryGanglion10.1
CingulateCortex40.3
Colorectaladenocarcinoma14.9
DorsalRootGanglion13.6
FetalThyroid13.8
Fetalbrain15
Fetalliver12.6
Fetallung12.45
GlobusPallidus30.85
Heart52.45
Hypothalamus20.25
Kidney12
Leukemia_chronicMyelogenousK-56213.45
Leukemia_promyelocytic-HL-6011.45
Leukemialymphoblastic(MOLT-4)11.2
Liver32.05
Lung37.05
Lymphnode10.65
Lymphoma_burkitts(Daudi)14.95
Lymphoma_burkitts(Raji)16.1
MedullaOblongata16.1
OccipitalLobe16.35
OlfactoryBulb13.55
Ovary9.7
Pancreas10.75
PancreaticIslet15.85
ParietalLobe19.2
Pituitary17.4
Placenta15.6
Pons21.8
PrefrontalCortex55.15
Prostate17.7
Salivarygland11.8
SkeletalMuscle17
Skin11.05
SmoothMuscle13.8
Spinalcord17.1
SubthalamicNucleus42.95
SuperiorCervicalGanglion16.3
TemporalLobe29.65
Testis11.25
TestisGermCell10.65
TestisIntersitial11.5
TestisLeydigCell14.6
TestisSeminiferousTubule12.1
Thalamus23.5
Thymus9.05
Thyroid31.8
Tongue14.9
Tonsil13.05
Trachea10.95
TrigeminalGanglion24.15
Uterus15.4
UterusCorpus13.05
WholeBlood9.1
Wholebrain28.25
colon11.85
pineal_day24.56
pineal_night25.2
retina26.4
small_intestine11.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_138_PI417507815
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.22 ± 0.48
Basal Forebrain7.07 ± 0.27
Basal Part of Pons6.98 ± 0.36
Cerebellar Cortex6.9 ± 0.19
Cerebellar Nuclei7.16 ± 0.36
Claustrum7.57 ± 0.59
Epithalamus6.69 ± 0.41
Frontal Lobe7.02 ± 0.33
Globus Pallidus7.25 ± 0.28
Hypothalamus6.99 ± 0.35
Insula6.97 ± 0.3
Limbic Lobe7.07 ± 0.42
Mesencephalon7.2 ± 0.36
Myelencephalon7.16 ± 0.38
Occipital Lobe7.33 ± 0.43
Parietal Lobe7.22 ± 0.39
Pontine Tegmentum7.03 ± 0.36
Striatum6.88 ± 0.36
Subthalamus7.16 ± 0.09
Temporal Lobe7.09 ± 0.34
Thalamus7.3 ± 0.28
White Matter7.15 ± 0.32
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfp358CBCerebellum100
100
Zfp358CTXCerebral cortex100
100
Zfp358HIPHippocampal region100
100
Zfp358HPFHippocampal formation100
100
Zfp358HYHypothalamus100
96.46
Zfp358LSXLateral septal complex100
81.12
Zfp358MBMidbrain100
100
Zfp358MYMedulla100
100
Zfp358OLFOlfactory bulb100
100
Zfp358PPons100
100
Zfp358PALPallidum100
98.02
Zfp358RHPRetrohippocampal region100
100
Zfp358sAMYStriatum-like amygdalar nuclei100
100
Zfp358STRStriatum100
100
Zfp358STRdStriatum dorsal region100
100
Zfp358STRvStriatum ventral region100
100
Zfp358THThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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