AutismKB 2.0

Annotation Detail for ZBTB46


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Basic Information Top
Gene Symbol:ZBTB46 ( BTBD4,FLJ13502,RINZF,ZNF340,dJ583P15.7,dJ583P15.8 )
Gene Full Name: zinc finger and BTB domain containing 46
Band: 20q13.33
Quick LinksEntrez ID:140685; OMIM: NA; Uniprot ID:Q6ZMU8_HUMAN; ENSEMBL ID: ENSG00000130584; HGNC ID: 16094
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus17 / 56401230
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult22 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal54 / 336030716
ovarian tumor5 / 7668265
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer5 / 10268048
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain12 / 110098910
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye5 / 21105423
heart0 / 896260 
intestine0 / 2344720 
kidney4 / 21177718
larynx0 / 241450 
liver0 / 2077430 
lung7 / 33697420
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary5 / 10205148
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta5 / 28082517
prostate6 / 18934531
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis5 / 33044215
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P518489
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.78 ± 1.22
Basal Forebrain2.39 ± 0.39
Basal Part of Pons2.5 ± 0.76
Cerebellar Cortex3.44 ± 0.48
Cerebellar Nuclei2.53 ± 0.72
Claustrum3.16 ± 0.87
Epithalamus2.52 ± 0.73
Frontal Lobe2.41 ± 0.88
Globus Pallidus2.31 ± 0.8
Hypothalamus2.94 ± 0.46
Insula2.16 ± 0.7
Limbic Lobe2.65 ± 0.85
Mesencephalon2.68 ± 0.8
Myelencephalon2.63 ± 0.81
Occipital Lobe2.58 ± 0.73
Parietal Lobe2.69 ± 0.91
Pontine Tegmentum2.65 ± 1.04
Striatum2.33 ± 0.89
Subthalamus3.06 ± 0.2
Temporal Lobe2.45 ± 1.06
Thalamus2.43 ± 0.78
White Matter1.93 ± 0.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Btbd4CBCerebellum84.06
100
Btbd4CTXCerebral cortex78.73
60.93
Btbd4HIPHippocampal region40.2
55.49
Btbd4HPFHippocampal formation52.19
61.9
Btbd4HYHypothalamus18.23
12.71
Btbd4LSXLateral septal complex49.66
36.56
Btbd4MBMidbrain15.41
13.32
Btbd4MYMedulla27.95
28.68
Btbd4OLFOlfactory bulb64
55.5
Btbd4PPons20.18
18.98
Btbd4PALPallidum20.6
16.39
Btbd4RHPRetrohippocampal region71.45
70.9
Btbd4sAMYStriatum-like amygdalar nuclei51.35
34.43
Btbd4STRStriatum39.9
29.05
Btbd4STRdStriatum dorsal region43.09
32.77
Btbd4STRvStriatum ventral region27.35
17.76
Btbd4THThalamus17.63
14.2
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018