AutismKB 2.0

Annotation Detail for TRIM69


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Basic Information Top
Gene Symbol:TRIM69 ( HSD34,RNF36,Trif )
Gene Full Name: tripartite motif-containing 69
Band: 15q15-q21
Quick LinksEntrez ID:140691; OMIM: NA; Uniprot ID:TRI69_HUMAN; ENSEMBL ID: ENSG00000185880; HGNC ID: 17857
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus18 / 56401231
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult85 / 193912143
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor4 / 11424635
esophageal tumor5 / 17290289
gastrointestinal tumor5 / 11936941
germ cell tumor9 / 26384534
glioma6 / 10688356
head and neck tumor1 / 1363027
kidney tumor5 / 6895972
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma3 / 7175541
non-neoplasia7 / 9725071
normal155 / 336030746
ovarian tumor5 / 7668265
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor11 / 12519187
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites2 / 4001549
bladder1 / 2975733
blood8 / 12347864
bone2 / 7165527
bone marrow0 / 488010 
brain75 / 110098968
cervix0 / 481710 
connective tissue13 / 14925587
ear1 / 1621261
embryonic tissue0 / 2157220 
esophagus5 / 20209247
eye2 / 2110549
heart2 / 8962622
intestine11 / 23447246
kidney9 / 21177742
larynx1 / 2414541
liver3 / 20774314
lung10 / 33697429
lymph1 / 4427022
lymph node3 / 9161032
mammary gland5 / 15327132
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary5 / 10205148
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta5 / 28082517
prostate4 / 18934521
salivary gland0 / 201550 
skin1 / 2105744
spleen14 / 53952259
stomach6 / 9661962
testis24 / 33044272
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus12 / 23287851
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9339_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.18 ± 0.51
Basal Forebrain4 ± 0.39
Basal Part of Pons3.9 ± 0.56
Cerebellar Cortex3.9 ± 0.41
Cerebellar Nuclei4.02 ± 0.32
Claustrum4.42 ± 0.63
Epithalamus3.27 ± 0.77
Frontal Lobe3.92 ± 0.56
Globus Pallidus3.31 ± 0.63
Hypothalamus3.37 ± 0.39
Insula3.99 ± 0.44
Limbic Lobe4.06 ± 0.54
Mesencephalon4.09 ± 0.77
Myelencephalon3.97 ± 0.61
Occipital Lobe4.24 ± 0.66
Parietal Lobe4.11 ± 0.51
Pontine Tegmentum4.01 ± 0.52
Striatum4.34 ± 0.6
Subthalamus3.72 ± 0.88
Temporal Lobe3.95 ± 0.6
Thalamus3.97 ± 0.64
White Matter2.76 ± 0.23
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rnf36CBCerebellum1.95
3.48
Rnf36CTXCerebral cortex2.34
2.7
Rnf36HIPHippocampal region1.24
1.09
Rnf36HPFHippocampal formation1.23
1.45
Rnf36HYHypothalamus0.1
0.07
Rnf36LSXLateral septal complex0.2
0.77
Rnf36MBMidbrain0.34
0.51
Rnf36MYMedulla1.42
1.73
Rnf36OLFOlfactory bulb2.32
1.64
Rnf36PPons0.59
0.82
Rnf36PALPallidum0.4
0.32
Rnf36RHPRetrohippocampal region1.16
1.47
Rnf36sAMYStriatum-like amygdalar nuclei1.58
1.12
Rnf36STRStriatum1.22
0.99
Rnf36STRdStriatum dorsal region1.09
0.99
Rnf36STRvStriatum ventral region1.84
1.11
Rnf36THThalamus4.17
5.47
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018