AutismKB 2.0

Annotation Detail for CRY1


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Basic Information Top
Gene Symbol:CRY1 ( PHLL1 )
Gene Full Name: cryptochrome 1 (photolyase-like)
Band: 12q23.3
Quick LinksEntrez ID:1407; OMIM: 601933; Uniprot ID:CRY1_HUMAN; ENSEMBL ID: ENSG00000008405; HGNC ID: 2384
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus27 / 56401247
neonate0 / 310970 
infant1 / 2362042
juvenile5 / 5555689
adult58 / 193912129
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor3 / 11424626
esophageal tumor1 / 1729057
gastrointestinal tumor5 / 11936941
germ cell tumor10 / 26384537
glioma0 / 1068830 
head and neck tumor4 / 13630229
kidney tumor1 / 6895914
leukemia5 / 9584252
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal108 / 336030732
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood4 / 12347832
bone2 / 7165527
bone marrow0 / 488010 
brain24 / 110098921
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus1 / 2020949
eye8 / 21105437
heart2 / 8962622
intestine4 / 23447217
kidney3 / 21177714
larynx2 / 2414582
liver9 / 20774343
lung4 / 33697411
lymph0 / 442700 
lymph node2 / 9161021
mammary gland1 / 1532716
mouth2 / 6705229
muscle4 / 10771537
nerve0 / 157680 
ovary2 / 10205119
pancreas5 / 21481223
parathyroid4 / 20539194
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta8 / 28082528
prostate1 / 1893455
salivary gland1 / 2015549
skin5 / 21057423
spleen1 / 5395218
stomach4 / 9661941
testis66 / 330442199
thymus8 / 8113198
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209674_at
Cell line Expression level Expression bar
721_B_lymphoblasts13.15
Adipocyte10.05
AdrenalCortex16.2
Adrenalgland12
Amygdala25.85
Appendix18.75
AtrioventricularNode20.05
BDCA4+_DentriticCells16.2
Bonemarrow13.7
BronchialEpithelialCells11.9
CD105+_Endothelial16
CD14+_Monocytes23.85
CD19+_BCells(neg._sel.)13.75
CD33+_Myeloid16.9
CD34+17.6
CD4+_Tcells30.35
CD56+_NKCells85.45
CD71+_EarlyErythroid17.05
CD8+_Tcells50.25
CardiacMyocytes26.3
Caudatenucleus12.15
Cerebellum38.15
CerebellumPeduncles50.7
CiliaryGanglion15.5
CingulateCortex12.1
Colorectaladenocarcinoma13.15
DorsalRootGanglion12.3
FetalThyroid23.55
Fetalbrain60.7
Fetalliver11.75
Fetallung58.05
GlobusPallidus10.05
Heart22.05
Hypothalamus17.85
Kidney11.05
Leukemia_chronicMyelogenousK-56217.55
Leukemia_promyelocytic-HL-6010
Leukemialymphoblastic(MOLT-4)46.65
Liver22.85
Lung17.9
Lymphnode9.9
Lymphoma_burkitts(Daudi)15.1
Lymphoma_burkitts(Raji)19.45
MedullaOblongata12.05
OccipitalLobe10.8
OlfactoryBulb10.6
Ovary11.25
Pancreas11.55
PancreaticIslet48.65
ParietalLobe15.2
Pituitary32.45
Placenta24.8
Pons12.9
PrefrontalCortex14.95
Prostate25.4
Salivarygland12.45
SkeletalMuscle24.45
Skin13.65
SmoothMuscle15.9
Spinalcord15.15
SubthalamicNucleus13.55
SuperiorCervicalGanglion25.6
TemporalLobe13.75
Testis91.2
TestisGermCell79.85
TestisIntersitial36.65
TestisLeydigCell31.8
TestisSeminiferousTubule44
Thalamus13.85
Thymus16.75
Thyroid74.9
Tongue17.5
Tonsil13.7
Trachea10.45
TrigeminalGanglion20
Uterus46.25
UterusCorpus16.4
WholeBlood22.85
Wholebrain20.75
colon18.1
pineal_day48
pineal_night46.06
retina31.2
small_intestine26.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P36665
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.12 ± 0.42
Basal Forebrain5.43 ± 0.21
Basal Part of Pons5.25 ± 0.27
Cerebellar Cortex5.81 ± 0.23
Cerebellar Nuclei5.24 ± 0.5
Claustrum5.14 ± 0.66
Epithalamus6 ± 0.54
Frontal Lobe5.17 ± 0.41
Globus Pallidus5.55 ± 0.6
Hypothalamus5.5 ± 0.52
Insula5.26 ± 0.28
Limbic Lobe5.15 ± 0.39
Mesencephalon5.41 ± 0.52
Myelencephalon5.33 ± 0.48
Occipital Lobe5.75 ± 0.39
Parietal Lobe5.26 ± 0.38
Pontine Tegmentum5.43 ± 0.42
Striatum5.46 ± 0.51
Subthalamus5.07 ± 0.36
Temporal Lobe5.22 ± 0.45
Thalamus5.53 ± 0.35
White Matter6.28 ± 0.31
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cry1CBCerebellum1.11
1.64
Cry1CTXCerebral cortex0.39
0.47
Cry1HIPHippocampal region1.09
1.13
Cry1HPFHippocampal formation0.77
0.9
Cry1HYHypothalamus0.04
0.14
Cry1LSXLateral septal complex0.14
0.16
Cry1MBMidbrain0.16
0.44
Cry1MYMedulla0.14
0.29
Cry1OLFOlfactory bulb0.94
1.86
Cry1PPons0.04
0.06
Cry1PALPallidum0.08
0.17
Cry1RHPRetrohippocampal region0.2
0.38
Cry1sAMYStriatum-like amygdalar nuclei0.09
0.25
Cry1STRStriatum0.12
0.17
Cry1STRdStriatum dorsal region0.12
0.15
Cry1STRvStriatum ventral region0.1
0.18
Cry1THThalamus0.19
0.21
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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