AutismKB 2.0

Annotation Detail for RIMS4


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Basic Information Top
Gene Symbol:RIMS4 ( C20orf190,RIM4,dJ781B1.3 )
Gene Full Name: regulating synaptic membrane exocytosis 4
Band: 20q13.12
Quick LinksEntrez ID:140730; OMIM: 611601; Uniprot ID:RIMS4_HUMAN; ENSEMBL ID: ENSG00000101098; HGNC ID: 16183
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst1 / 6231916
fetus27 / 56401247
neonate0 / 310970 
infant6 / 23620254
juvenile0 / 555560 
adult16 / 19391218
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor2 / 3436658
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor8 / 26384530
glioma3 / 10688328
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal90 / 336030726
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS19 / 125680151
prostate cancer0 / 1026800 
retinoblastoma3 / 4635664
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain77 / 110098969
cervix2 / 4817141
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine1 / 2344724
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung9 / 33697426
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis18 / 33044254
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P374532
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.12 ± 0.65
Basal Forebrain4.44 ± 0.8
Basal Part of Pons5.11 ± 0.51
Cerebellar Cortex4.54 ± 0.4
Cerebellar Nuclei4.49 ± 0.58
Claustrum5.38 ± 0.79
Epithalamus4.05 ± 0.54
Frontal Lobe4.66 ± 0.54
Globus Pallidus3.62 ± 0.57
Hypothalamus4.37 ± 0.63
Insula4.61 ± 0.6
Limbic Lobe5.04 ± 0.47
Mesencephalon4.7 ± 0.62
Myelencephalon4.84 ± 0.69
Occipital Lobe5.23 ± 0.53
Parietal Lobe5.01 ± 0.53
Pontine Tegmentum4.66 ± 0.53
Striatum5.57 ± 0.48
Subthalamus4.77 ± 0.83
Temporal Lobe4.88 ± 0.45
Thalamus4.59 ± 0.54
White Matter2.84 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rims4CBCerebellum4.95
5.02
Rims4CTXCerebral cortex2.79
2.22
Rims4HIPHippocampal region7.87
8.17
Rims4HPFHippocampal formation6.6
6.16
Rims4HYHypothalamus0.15
0.1
Rims4LSXLateral septal complex1.27
1.15
Rims4MBMidbrain0.15
0.17
Rims4MYMedulla3.57
4.24
Rims4OLFOlfactory bulb6.88
6
Rims4PPons0.31
0.42
Rims4PALPallidum0.15
0.1
Rims4RHPRetrohippocampal region4.56
3.42
Rims4sAMYStriatum-like amygdalar nuclei1.12
0.66
Rims4STRStriatum0.54
0.46
Rims4STRdStriatum dorsal region0.49
0.48
Rims4STRvStriatum ventral region0.05
0.03
Rims4THThalamus0.56
0.53
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018