Annotation Detail for SMCR8
Basic Information Top
| Gene Symbol: | SMCR8 ( FLJ34716,FLJ60657 ) |
|---|---|
| Gene Full Name: | Smith-Magenis syndrome chromosome region, candidate 8 |
| Band: | 17p11.2 |
| Quick Links | Entrez ID:140775; OMIM: NA; Uniprot ID:SMCR8_HUMAN; ENSEMBL ID: ENSG00000176994; HGNC ID: 17921 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.592944
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 1 / 62319 | 16 | |
| fetus | 34 / 564012 | 60 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 1 / 23620 | 42 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 109 / 1939121 | 56 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 1 / 12794 | 78 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 8 / 94178 | 84 | |
| cervical tumor | 2 / 34366 | 58 | |
| chondrosarcoma | 6 / 82823 | 72 | |
| colorectal tumor | 19 / 114246 | 166 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 5 / 119369 | 41 | |
| germ cell tumor | 5 / 263845 | 18 | |
| glioma | 2 / 106883 | 18 | |
| head and neck tumor | 14 / 136302 | 102 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 5 / 95842 | 52 | |
| liver tumor | 12 / 96359 | 124 | |
| lung tumor | 1 / 103127 | 9 |  |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 137 / 3360307 | 40 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 2 / 125680 | 15 | |
| prostate cancer | 6 / 102680 | 58 | |
| retinoblastoma | 6 / 46356 | 129 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 2 / 125191 | 15 | |
| uterine tumor | 2 / 90257 | 22 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 0 / 29757 | 0 | |
| blood | 5 / 123478 | 40 | |
| bone | 5 / 71655 | 69 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 12 / 1100989 | 10 | |
| cervix | 3 / 48171 | 62 | |
| connective tissue | 5 / 149255 | 33 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 5 / 215722 | 23 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 10 / 211054 | 47 | |
| heart | 0 / 89626 | 0 | |
| intestine | 22 / 234472 | 93 | |
| kidney | 14 / 211777 | 66 | |
| larynx | 1 / 24145 | 41 | |
| liver | 26 / 207743 | 125 | |
| lung | 10 / 336974 | 29 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 4 / 91610 | 43 | |
| mammary gland | 14 / 153271 | 91 | |
| mouth | 5 / 67052 | 74 | |
| muscle | 4 / 107715 | 37 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 4 / 102051 | 39 | |
| pancreas | 3 / 214812 | 13 | |
| parathyroid | 3 / 20539 | 146 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 9 / 280825 | 32 | |
| prostate | 7 / 189345 | 36 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 12 / 210574 | 56 | |
| spleen | 5 / 53952 | 92 | |
| stomach | 11 / 96619 | 113 | |
| testis | 3 / 330442 | 9 | |
| thymus | 3 / 81131 | 36 | |
| thyroid | 10 / 47473 | 210 |  |
| tonsil | 0 / 16999 | 0 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 5 / 232878 | 21 | |
| vascular | 1 / 51780 | 19 | |
Microarray in - Probe name: CUST_178_PI417507815
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.17 ± 1.15 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.74 ± 0.52 | |
| Basal Part of Pons | 1.51 ± 0.92 | |
| Cerebellar Cortex | 2.01 ± 0.8 | |
| Cerebellar Nuclei | 1.94 ± 0.69 | |
| Claustrum | 2.48 ± 0.83 | |
| Epithalamus | 1.5 ± 0.71 | |
| Frontal Lobe | 1.59 ± 0.75 | |
| Globus Pallidus | 1.63 ± 0.4 | |
| Hypothalamus | 1.66 ± 0.79 | |
| Insula | 1.14 ± 0.46 | |
| Limbic Lobe | 1.72 ± 0.72 | |
| Mesencephalon | 1.76 ± 0.74 | |
| Myelencephalon | 1.77 ± 0.79 | |
| Occipital Lobe | 2.15 ± 0.91 | |
| Parietal Lobe | 1.79 ± 0.82 | |
| Pontine Tegmentum | 1.73 ± 0.7 | |
| Striatum | 1.64 ± 0.81 | |
| Subthalamus | 1.78 ± 0.67 | |
| Temporal Lobe | 1.7 ± 0.84 | |
| Thalamus | 1.66 ± 0.86 | |
| White Matter | 2.19 ± 0.91 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Smcr8 | CB | Cerebellum | 32.52 | |
| 55.73 | | |||
| Smcr8 | CTX | Cerebral cortex | 80.11 | |
| 70.07 | | |||
| Smcr8 | HIP | Hippocampal region | 43.78 | |
| 68.46 | | |||
| Smcr8 | HPF | Hippocampal formation | 52.15 | |
| 64.57 | | |||
| Smcr8 | HY | Hypothalamus | 16 | |
| 15.68 | | |||
| Smcr8 | LSX | Lateral septal complex | 5.29 | |
| 4.15 | | |||
| Smcr8 | MB | Midbrain | 28.94 | |
| 31.63 | | |||
| Smcr8 | MY | Medulla | 46.15 | |
| 57.67 | | |||
| Smcr8 | OLF | Olfactory bulb | 60.37 | |
| 57.84 | | |||
| Smcr8 | P | Pons | 31.04 | |
| 38.62 | | |||
| Smcr8 | PAL | Pallidum | 29.42 | |
| 36.2 | | |||
| Smcr8 | RHP | Retrohippocampal region | 68.78 | |
| 62.16 | | |||
| Smcr8 | sAMY | Striatum-like amygdalar nuclei | 56.33 | |
| 50.15 | | |||
| Smcr8 | STR | Striatum | 32.11 | |
| 27.16 | | |||
| Smcr8 | STRd | Striatum dorsal region | 30.45 | |
| 25.2 | | |||
| Smcr8 | STRv | Striatum ventral region | 40.25 | |
| 33.88 | | |||
| Smcr8 | TH | Thalamus | 42.49 | |
| 46.51 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00500695 | 29 | 590 | 618 | ESDGQLVLPSTPAHTHSDEDGVVSSPPQR | Peptide Atlas |