AutismKB 2.0

Annotation Detail for CRY2


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Basic Information Top
Gene Symbol:CRY2 ( FLJ10332,HCRY2,KIAA0658,PHLL2 )
Gene Full Name: cryptochrome 2 (photolyase-like)
Band: 11p11.2
Quick LinksEntrez ID:1408; OMIM: 603732; Uniprot ID:CRY2_HUMAN; ENSEMBL ID: ENSG00000121671; HGNC ID: 2385
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst3 / 6231948
fetus51 / 56401290
neonate0 / 310970 
infant1 / 2362042
juvenile2 / 5555635
adult137 / 193912170
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor16 / 119369134
germ cell tumor15 / 26384556
glioma16 / 106883149
head and neck tumor21 / 136302154
kidney tumor1 / 6895914
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal381 / 3360307113
ovarian tumor3 / 7668239
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites16 / 40015399
bladder1 / 2975733
blood2 / 12347816
bone1 / 7165513
bone marrow3 / 4880161
brain283 / 1100989257
cervix0 / 481710 
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye18 / 21105485
heart4 / 8962644
intestine5 / 23447221
kidney3 / 21177714
larynx1 / 2414541
liver7 / 20774333
lung18 / 33697453
lymph0 / 442700 
lymph node2 / 9161021
mammary gland8 / 15327152
mouth18 / 67052268
muscle5 / 10771546
nerve1 / 1576863
ovary3 / 10205129
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland1 / 1658560
placenta8 / 28082528
prostate6 / 18934531
salivary gland0 / 201550 
skin3 / 21057414
spleen4 / 5395274
stomach0 / 966190 
testis64 / 330442193
thymus10 / 81131123
thyroid4 / 4747384
tonsil0 / 169990 
trachea19 / 52413362
umbilical cord0 / 136800 
uterus23 / 23287898
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212695_at
Cell line Expression level Expression bar
721_B_lymphoblasts20.35
Adipocyte26.95
AdrenalCortex31.5
Adrenalgland23.55
Amygdala31.4
Appendix36.65
AtrioventricularNode21.15
BDCA4+_DentriticCells20.7
Bonemarrow27.05
BronchialEpithelialCells16.85
CD105+_Endothelial27.65
CD14+_Monocytes24.8
CD19+_BCells(neg._sel.)28.85
CD33+_Myeloid32.55
CD34+30.3
CD4+_Tcells25.45
CD56+_NKCells31.8
CD71+_EarlyErythroid25.75
CD8+_Tcells26.15
CardiacMyocytes26.9
Caudatenucleus25.15
Cerebellum33.05
CerebellumPeduncles60.45
CiliaryGanglion20.65
CingulateCortex28.75
Colorectaladenocarcinoma27.3
DorsalRootGanglion22.2
FetalThyroid26.8
Fetalbrain27.75
Fetalliver24.05
Fetallung22.75
GlobusPallidus22.1
Heart42.95
Hypothalamus39.05
Kidney22.8
Leukemia_chronicMyelogenousK-56224.8
Leukemia_promyelocytic-HL-6022.6
Leukemialymphoblastic(MOLT-4)21.25
Liver38.6
Lung31.45
Lymphnode23.4
Lymphoma_burkitts(Daudi)34.95
Lymphoma_burkitts(Raji)33.5
MedullaOblongata32.25
OccipitalLobe25.15
OlfactoryBulb21.9
Ovary18.65
Pancreas22.45
PancreaticIslet29.75
ParietalLobe30.65
Pituitary32.45
Placenta27.7
Pons35.2
PrefrontalCortex42.2
Prostate32.3
Salivarygland22.4
SkeletalMuscle37.55
Skin25.45
SmoothMuscle31.25
Spinalcord29.6
SubthalamicNucleus27.45
SuperiorCervicalGanglion36.25
TemporalLobe35.75
Testis24
TestisGermCell32.85
TestisIntersitial27
TestisLeydigCell28.65
TestisSeminiferousTubule24.05
Thalamus28.55
Thymus21.5
Thyroid38.15
Tongue27.85
Tonsil26.85
Trachea23.15
TrigeminalGanglion29.6
Uterus22.95
UterusCorpus25.85
WholeBlood30
Wholebrain32.5
colon27.7
pineal_day239.96
pineal_night474.52
retina60.65
small_intestine25.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P127394
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.84 ± 0.26
Basal Forebrain9.58 ± 0.15
Basal Part of Pons9.6 ± 0.21
Cerebellar Cortex9.99 ± 0.15
Cerebellar Nuclei8.98 ± 0.33
Claustrum10.11 ± 0.19
Epithalamus9.45 ± 0.3
Frontal Lobe9.85 ± 0.32
Globus Pallidus8.98 ± 0.22
Hypothalamus9.4 ± 0.3
Insula10.16 ± 0.29
Limbic Lobe10.01 ± 0.25
Mesencephalon9.76 ± 0.31
Myelencephalon9.79 ± 0.31
Occipital Lobe9.7 ± 0.36
Parietal Lobe9.81 ± 0.25
Pontine Tegmentum9.69 ± 0.31
Striatum9.57 ± 0.36
Subthalamus9.52 ± 0.17
Temporal Lobe9.95 ± 0.24
Thalamus9.74 ± 0.3
White Matter8.55 ± 0.29
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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