AutismKB 2.0

Annotation Detail for ZNF280B


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Basic Information Top
Gene Symbol:ZNF280B ( 5'OY11.1,D87009.C22.3,SUHW2,ZNF279,ZNF632 )
Gene Full Name: zinc finger protein 280B
Band: 22q11.22
Quick LinksEntrez ID:140883; OMIM: NA; Uniprot ID:Z280B_HUMAN; ENSEMBL ID: ENSG00000198477; HGNC ID: 23022
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus13 / 56401223
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult11 / 19391215
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal55 / 336030716
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain9 / 11009898
cervix0 / 481710 
connective tissue0 / 1492550 
ear2 / 16212123
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine4 / 23447217
kidney1 / 2117774
larynx0 / 241450 
liver2 / 2077439
lung0 / 3369740 
lymph0 / 442700 
lymph node2 / 9161021
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin11 / 21057452
spleen0 / 539520 
stomach1 / 9661910
testis39 / 330442118
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215048_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.55
Adipocyte6.9
AdrenalCortex7.95
Adrenalgland6.25
Amygdala7.15
Appendix8.75
AtrioventricularNode6.9
BDCA4+_DentriticCells6.6
Bonemarrow7
BronchialEpithelialCells6.75
CD105+_Endothelial6.75
CD14+_Monocytes7.35
CD19+_BCells(neg._sel.)7.05
CD33+_Myeloid8.15
CD34+8.15
CD4+_Tcells7.3
CD56+_NKCells7.7
CD71+_EarlyErythroid6.55
CD8+_Tcells6.2
CardiacMyocytes11.5
Caudatenucleus6.2
Cerebellum5.75
CerebellumPeduncles8.35
CiliaryGanglion5.95
CingulateCortex7.3
Colorectaladenocarcinoma6.95
DorsalRootGanglion5.5
FetalThyroid6.9
Fetalbrain6.75
Fetalliver6.15
Fetallung5.5
GlobusPallidus5.1
Heart11.4
Hypothalamus7.25
Kidney6.4
Leukemia_chronicMyelogenousK-5626.3
Leukemia_promyelocytic-HL-606.15
Leukemialymphoblastic(MOLT-4)6.45
Liver10.45
Lung7.5
Lymphnode6.05
Lymphoma_burkitts(Daudi)8.9
Lymphoma_burkitts(Raji)10.7
MedullaOblongata6.25
OccipitalLobe6.2
OlfactoryBulb5.35
Ovary5.65
Pancreas5.8
PancreaticIslet7.45
ParietalLobe7.75
Pituitary8.15
Placenta7.1
Pons6.9
PrefrontalCortex8.3
Prostate7.95
Salivarygland5.65
SkeletalMuscle8.85
Skin5.8
SmoothMuscle8.55
Spinalcord7.4
SubthalamicNucleus6.35
SuperiorCervicalGanglion9.5
TemporalLobe6.35
Testis17.6
TestisGermCell30.2
TestisIntersitial128.3
TestisLeydigCell12.75
TestisSeminiferousTubule14.2
Thalamus7.1
Thymus5.45
Thyroid8.75
Tongue7.95
Tonsil6.95
Trachea5.7
TrigeminalGanglion6.95
Uterus5.65
UterusCorpus6.65
WholeBlood7.55
Wholebrain5.6
colon6.95
pineal_day8.34
pineal_night8.16
retina8.35
small_intestine6.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P402134
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.46 ± 0.28
Basal Forebrain8.1 ± 0.27
Basal Part of Pons8.27 ± 0.23
Cerebellar Cortex8.11 ± 0.31
Cerebellar Nuclei8.31 ± 0.33
Claustrum8.47 ± 0.45
Epithalamus7.86 ± 0.4
Frontal Lobe8.07 ± 0.32
Globus Pallidus7.64 ± 0.2
Hypothalamus8.38 ± 0.34
Insula8.04 ± 0.31
Limbic Lobe8.21 ± 0.36
Mesencephalon8.23 ± 0.36
Myelencephalon8.14 ± 0.33
Occipital Lobe8.49 ± 0.28
Parietal Lobe8.26 ± 0.27
Pontine Tegmentum8.16 ± 0.3
Striatum8.18 ± 0.28
Subthalamus8.52 ± 0.23
Temporal Lobe8.14 ± 0.25
Thalamus8.02 ± 0.26
White Matter7.13 ± 0.34
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Suhw2CBCerebellum17
18.95
Suhw2CTXCerebral cortex31.09
21.59
Suhw2HIPHippocampal region26.45
26.7
Suhw2HPFHippocampal formation31.83
28.01
Suhw2HYHypothalamus5.74
4.26
Suhw2LSXLateral septal complex2.45
1.45
Suhw2MBMidbrain5.88
6.06
Suhw2MYMedulla7.77
7.38
Suhw2OLFOlfactory bulb25.77
18.87
Suhw2PPons5.65
5.33
Suhw2PALPallidum5.63
4.42
Suhw2RHPRetrohippocampal region42.81
31.27
Suhw2sAMYStriatum-like amygdalar nuclei10.34
6.87
Suhw2STRStriatum16.9
11.44
Suhw2STRdStriatum dorsal region21.55
14.97
Suhw2STRvStriatum ventral region7.58
4.52
Suhw2THThalamus6.62
4.97
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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