AutismKB 2.0

Annotation Detail for MIB2


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Basic Information Top
Gene Symbol:MIB2 ( FLJ20648,FLJ39787,FLJ41406,ZZANK1,ZZZ5 )
Gene Full Name: mindbomb homolog 2 (Drosophila)
Band: 1p36.33
Quick LinksEntrez ID:142678; OMIM: 611141; Uniprot ID:MIB2_HUMAN; ENSEMBL ID: ENSG00000197530; HGNC ID: 30577
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst2 / 6231932
fetus22 / 56401239
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult67 / 193912134
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus12 / 56401221
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult37 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor3 / 3436687
chondrosarcoma1 / 8282312
colorectal tumor5 / 11424643
esophageal tumor1 / 1729057
gastrointestinal tumor4 / 11936933
germ cell tumor12 / 26384545
glioma5 / 10688346
head and neck tumor6 / 13630244
kidney tumor6 / 6895987
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor5 / 10312748
lymphoma3 / 7175541
non-neoplasia3 / 9725030
normal108 / 336030732
ovarian tumor4 / 7668252
pancreatic tumor44 / 104616420
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer5 / 10268048
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor3 / 9025733
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor2 / 2638457
glioma4 / 10688337
head and neck tumor5 / 13630236
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal50 / 336030714
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites2 / 4001549
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow2 / 4880140
brain42 / 110098938
cervix7 / 48171145
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus1 / 2020949
eye7 / 21105433
heart2 / 8962622
intestine12 / 23447251
kidney8 / 21177737
larynx0 / 241450 
liver0 / 2077430 
lung11 / 33697432
lymph3 / 4427067
lymph node0 / 916100 
mammary gland3 / 15327119
mouth4 / 6705259
muscle1 / 1077159
nerve2 / 15768126
ovary8 / 10205178
pancreas46 / 214812214
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta9 / 28082532
prostate11 / 18934558
salivary gland2 / 2015599
skin5 / 21057423
spleen2 / 5395237
stomach6 / 9661962
testis12 / 33044236
thymus11 / 81131135
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain21 / 110098919
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye2 / 2110549
heart4 / 8962644
intestine1 / 2344724
kidney3 / 21177714
larynx0 / 241450 
liver1 / 2077434
lung13 / 33697438
lymph0 / 442700 
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth3 / 6705244
muscle4 / 10771537
nerve0 / 157680 
ovary1 / 1020519
pancreas1 / 2148124
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta1 / 2808253
prostate8 / 18934542
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach1 / 9661910
testis6 / 33044218
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7247_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.3 ± 0.38
Basal Forebrain5.08 ± 0.24
Basal Part of Pons5.15 ± 0.3
Cerebellar Cortex5.25 ± 0.48
Cerebellar Nuclei5.03 ± 0.29
Claustrum5.31 ± 0.49
Epithalamus4.77 ± 0.42
Frontal Lobe5.08 ± 0.41
Globus Pallidus4.93 ± 0.36
Hypothalamus4.71 ± 0.38
Insula5.06 ± 0.35
Limbic Lobe5.19 ± 0.55
Mesencephalon5.07 ± 0.37
Myelencephalon5.14 ± 0.45
Occipital Lobe5.29 ± 0.45
Parietal Lobe5.12 ± 0.48
Pontine Tegmentum5.03 ± 0.49
Striatum5.02 ± 0.39
Subthalamus4.87 ± 0.81
Temporal Lobe5.07 ± 0.45
Thalamus5.07 ± 0.38
White Matter4.45 ± 0.15
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mib2CBCerebellum67.97
88.57
Mib2CTXCerebral cortex100
100
Mib2HIPHippocampal region94.43
100
Mib2HPFHippocampal formation100
100
Mib2HYHypothalamus89.32
78.26
Mib2LSXLateral septal complex88.55
67.84
Mib2MBMidbrain89.67
82.83
Mib2MYMedulla72.12
77.23
Mib2OLFOlfactory bulb88.9
77.82
Mib2PPons71.54
73.81
Mib2PALPallidum87.41
82.62
Mib2RHPRetrohippocampal region100
100
Mib2sAMYStriatum-like amygdalar nuclei100
100
Mib2STRStriatum100
89.82
Mib2STRdStriatum dorsal region100
92.79
Mib2STRvStriatum ventral region100
85.6
Mib2THThalamus100
96.53
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018