AutismKB 2.0

Annotation Detail for CRYM


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Basic Information Top
Gene Symbol:CRYM ( DFNA40,THBP )
Gene Full Name: crystallin, mu
Band: 16p12.2
Quick LinksEntrez ID:1428; OMIM: 123740; Uniprot ID:CRYM_HUMAN; ENSEMBL ID: ENSG00000103316; HGNC ID: 2418
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus18 / 56401231
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult34 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor2 / 2638457
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal80 / 336030723
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain53 / 110098948
cervix0 / 481710 
connective tissue0 / 1492550 
ear5 / 16212308
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye7 / 21105433
heart1 / 8962611
intestine1 / 2344724
kidney4 / 21177718
larynx1 / 2414541
liver0 / 2077430 
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle5 / 10771546
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland4 / 16585241
placenta0 / 2808250 
prostate8 / 18934542
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis5 / 33044215
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205489_at
Cell line Expression level Expression bar
721_B_lymphoblasts13.55
Adipocyte10.35
AdrenalCortex10.7
Adrenalgland8.65
Amygdala214.6
Appendix13.6
AtrioventricularNode15.35
BDCA4+_DentriticCells46.6
Bonemarrow10.25
BronchialEpithelialCells8.2
CD105+_Endothelial9.3
CD14+_Monocytes9.5
CD19+_BCells(neg._sel.)10.45
CD33+_Myeloid10.95
CD34+13.3
CD4+_Tcells10.95
CD56+_NKCells10.95
CD71+_EarlyErythroid7
CD8+_Tcells9.85
CardiacMyocytes13.45
Caudatenucleus149.3
Cerebellum191.4
CerebellumPeduncles246.4
CiliaryGanglion14.6
CingulateCortex147.35
Colorectaladenocarcinoma9.6
DorsalRootGanglion8.2
FetalThyroid10.1
Fetalbrain107.25
Fetalliver9
Fetallung10.45
GlobusPallidus88.45
Heart370.55
Hypothalamus31.25
Kidney67.65
Leukemia_chronicMyelogenousK-5629.55
Leukemia_promyelocytic-HL-609.3
Leukemialymphoblastic(MOLT-4)8.6
Liver16.85
Lung11.75
Lymphnode8.85
Lymphoma_burkitts(Daudi)17.85
Lymphoma_burkitts(Raji)13.05
MedullaOblongata91.65
OccipitalLobe260.6
OlfactoryBulb8.1
Ovary7.05
Pancreas8.15
PancreaticIslet11.75
ParietalLobe113.4
Pituitary213.15
Placenta10.7
Pons96.9
PrefrontalCortex124.25
Prostate114.6
Salivarygland15.2
SkeletalMuscle11.55
Skin8.9
SmoothMuscle12.05
Spinalcord11.3
SubthalamicNucleus97.9
SuperiorCervicalGanglion12.1
TemporalLobe152.8
Testis13.1
TestisGermCell11
TestisIntersitial12.5
TestisLeydigCell12.1
TestisSeminiferousTubule9
Thalamus18.55
Thymus8.25
Thyroid12.3
Tongue10.5
Tonsil10.15
Trachea32.15
TrigeminalGanglion11.6
Uterus8.4
UterusCorpus9.15
WholeBlood10.8
Wholebrain649.5
colon9.75
pineal_day13.2
pineal_night12.36
retina12.775
small_intestine8.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11733_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.31 ± 0.73
Basal Forebrain6.21 ± 1.23
Basal Part of Pons5.52 ± 0.94
Cerebellar Cortex6.84 ± 0.4
Cerebellar Nuclei5.56 ± 0.79
Claustrum4.71 ± 1.55
Epithalamus5.49 ± 0.75
Frontal Lobe6.61 ± 0.83
Globus Pallidus3.16 ± 0.8
Hypothalamus7.06 ± 1.39
Insula6.83 ± 0.43
Limbic Lobe6.53 ± 1.34
Mesencephalon5.81 ± 0.82
Myelencephalon5.94 ± 0.84
Occipital Lobe4.62 ± 1.52
Parietal Lobe6.14 ± 0.94
Pontine Tegmentum6.38 ± 1.01
Striatum6.25 ± 1.14
Subthalamus5.66 ± 0.25
Temporal Lobe6.67 ± 0.99
Thalamus5.18 ± 0.92
White Matter3.34 ± 0.83
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
CrymCBCerebellum4.26
6.82
CrymCTXCerebral cortex71.68
85.42
CrymHIPHippocampal region100
100
CrymHPFHippocampal formation100
100
CrymHYHypothalamus3.64
4.76
CrymLSXLateral septal complex33.49
60.77
CrymMBMidbrain2.52
3.14
CrymMYMedulla1.78
2.29
CrymOLFOlfactory bulb58.99
77.02
CrymPPons2.93
3.11
CrymPALPallidum15.17
22.19
CrymRHPRetrohippocampal region100
100
CrymsAMYStriatum-like amygdalar nuclei35.36
46.38
CrymSTRStriatum68.19
79.24
CrymSTRdStriatum dorsal region52.5
61.1
CrymSTRvStriatum ventral region100
100
CrymTHThalamus8.53
13.89
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CRYM_HUMAN_120 10 120 129 TAAVSAIATK PRIDE
CRYM_HUMAN_130 36 130 165 FLKPPSSEVLCILGAGVQAYSHYEIFTEQFSFKEVR PRIDE
CRYM_HUMAN_177 10 177 186 FADTVQGEVR PRIDE
CRYM_HUMAN_19 29 19 47 SSSLLIPPLETALANFSSGPEGGVMQPVR PRIDE
CRYM_HUMAN_243 14 243 256 EAVLYVDSQEAALK PRIDE
CRYM_HUMAN_278 9 278 286 GVKPAHCEK PRIDE
CRYM_HUMAN_292 13 292 304 SLGMAVEDTVAAK PRIDE
CRYM_HUMAN_305 10 305 314 LIYDSWSSGK PRIDE
CRYM_HUMAN_4 15 4 18 VPAFLSAAEVEEHLR PRIDE
CRYM_HUMAN_57 19 57 75 GYLGVMPAYSAAEDALTTK PRIDE
CRYM_HUMAN_76 8 76 83 LVTFYEDR PRIDE
PAp00069077 9 278 286 GVKPAHCEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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