AutismKB 2.0

Annotation Detail for CRYZ


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Basic Information Top
Gene Symbol:CRYZ ( DKFZp779E0834,FLJ41475 )
Gene Full Name: crystallin, zeta (quinone reductase)
Band: 1p31.1
Quick LinksEntrez ID:1429; OMIM: 123691; Uniprot ID:QOR_HUMAN; ENSEMBL ID: ENSG00000116791; HGNC ID: 2419
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst2 / 6231932
fetus21 / 56401237
neonate2 / 3109764
infant1 / 2362042
juvenile0 / 555560 
adult93 / 193912147
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma3 / 17475171
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma8 / 8282396
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor9 / 11936975
germ cell tumor13 / 26384549
glioma2 / 10688318
head and neck tumor5 / 13630236
kidney tumor9 / 68959130
leukemia10 / 95842104
liver tumor21 / 96359217
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia6 / 9725061
normal192 / 336030757
ovarian tumor3 / 7668239
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland4 / 33197120
ascites4 / 4001599
bladder8 / 29757268
blood6 / 12347848
bone4 / 7165555
bone marrow8 / 48801163
brain45 / 110098940
cervix2 / 4817141
connective tissue12 / 14925580
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye6 / 21105428
heart11 / 89626122
intestine13 / 23447255
kidney39 / 211777184
larynx0 / 241450 
liver48 / 207743231
lung7 / 33697420
lymph0 / 442700 
lymph node5 / 9161054
mammary gland0 / 1532710 
mouth4 / 6705259
muscle2 / 10771518
nerve0 / 157680 
ovary4 / 10205139
pancreas12 / 21481255
parathyroid4 / 20539194
pharynx6 / 41328145
pituitary gland4 / 16585241
placenta7 / 28082524
prostate5 / 18934526
salivary gland1 / 2015549
skin3 / 21057414
spleen1 / 5395218
stomach5 / 9661951
testis8 / 33044224
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord2 / 13680146
uterus27 / 232878115
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202950_at
Cell line Expression level Expression bar
721_B_lymphoblasts540.7
Adipocyte23.4
AdrenalCortex10.25
Adrenalgland10.65
Amygdala24.75
Appendix13.15
AtrioventricularNode6.15
BDCA4+_DentriticCells41.65
Bonemarrow6.45
BronchialEpithelialCells96.35
CD105+_Endothelial7.4
CD14+_Monocytes14.2
CD19+_BCells(neg._sel.)14.95
CD33+_Myeloid9.55
CD34+36.95
CD4+_Tcells36
CD56+_NKCells81.4
CD71+_EarlyErythroid4.85
CD8+_Tcells19.75
CardiacMyocytes21.25
Caudatenucleus7
Cerebellum4.85
CerebellumPeduncles8.65
CiliaryGanglion6.1
CingulateCortex9.35
Colorectaladenocarcinoma7.75
DorsalRootGanglion8.25
FetalThyroid10.55
Fetalbrain7.4
Fetalliver192.35
Fetallung69.05
GlobusPallidus4.8
Heart9.85
Hypothalamus32.4
Kidney135.35
Leukemia_chronicMyelogenousK-56273.45
Leukemia_promyelocytic-HL-60154.1
Leukemialymphoblastic(MOLT-4)14.9
Liver11.3
Lung6.35
Lymphnode22.3
Lymphoma_burkitts(Daudi)37.95
Lymphoma_burkitts(Raji)53.2
MedullaOblongata6.9
OccipitalLobe12.95
OlfactoryBulb12.95
Ovary7.05
Pancreas63.65
PancreaticIslet126.05
ParietalLobe8.75
Pituitary32.5
Placenta6
Pons7.65
PrefrontalCortex22.45
Prostate41.3
Salivarygland10.35
SkeletalMuscle10
Skin7.9
SmoothMuscle26.35
Spinalcord21.05
SubthalamicNucleus7.45
SuperiorCervicalGanglion15.2
TemporalLobe7.35
Testis6.2
TestisGermCell6.35
TestisIntersitial8.55
TestisLeydigCell8.25
TestisSeminiferousTubule6.6
Thalamus13.65
Thymus7.3
Thyroid134.6
Tongue8.65
Tonsil10.75
Trachea20.75
TrigeminalGanglion12.3
Uterus77.9
UterusCorpus7.2
WholeBlood9.25
Wholebrain7.1
colon11.8
pineal_day120.02
pineal_night143.24
retina45.525
small_intestine88.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P114662
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.73 ± 0.3
Basal Forebrain6.75 ± 0.33
Basal Part of Pons6.79 ± 0.18
Cerebellar Cortex6.28 ± 0.34
Cerebellar Nuclei6.69 ± 0.29
Claustrum6.95 ± 0.61
Epithalamus7.26 ± 0.18
Frontal Lobe7.07 ± 0.4
Globus Pallidus6.93 ± 0.66
Hypothalamus7.42 ± 0.32
Insula7.16 ± 0.33
Limbic Lobe6.67 ± 0.7
Mesencephalon6.83 ± 0.49
Myelencephalon6.82 ± 0.56
Occipital Lobe6.39 ± 0.5
Parietal Lobe6.68 ± 0.46
Pontine Tegmentum6.95 ± 0.58
Striatum6.14 ± 0.82
Subthalamus7.17 ± 0.21
Temporal Lobe6.95 ± 0.37
Thalamus7.09 ± 0.45
White Matter6.64 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
CryzCBCerebellum0.09
0.29
CryzCTXCerebral cortex0.27
0.84
CryzHIPHippocampal region0.06
0.14
CryzHPFHippocampal formation0.07
0.16
CryzHYHypothalamus0.23
1.29
CryzLSXLateral septal complex0.22
0.78
CryzMBMidbrain0.09
0.38
CryzMYMedulla0.09
0.37
CryzOLFOlfactory bulb0.44
1.69
CryzPPons0.14
0.43
CryzPALPallidum0.03
0.02
CryzRHPRetrohippocampal region0.04
0.16
CryzsAMYStriatum-like amygdalar nuclei0
0
CryzSTRStriatum0.13
0.16
CryzSTRdStriatum dorsal region0.08
0.1
CryzSTRvStriatum ventral region0.35
0.24
CryzTHThalamus0.08
0.39
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000349 23 148 170 AGESVLVHGASGGVGLAACQIAR Peptide Atlas
QOR_HUMAN_0 0 0 0 DLSLLSHGGR PRIDE
QOR_HUMAN_0 0 0 0 KPLLPYTPGSDVAGVIEAVGDNASAFK PRIDE
QOR_HUMAN_0 0 0 0 VAEAHENIIHGSGATGK PRIDE
QOR_HUMAN_12 11 12 22 VFEFGGPEVLK PRIDE
QOR_HUMAN_13 11 13 23 VFEFGGPEVLK PRIDE
QOR_HUMAN_176 12 176 187 ILGTAGTEEGQK PRIDE
QOR_HUMAN_2 8 2 9 ATGQKLMR PRIDE
QOR_HUMAN_232 10 232 241 DLSLLSHGGR PRIDE
QOR_HUMAN_307 17 307 323 VAEAHENIIHGSGATGK PRIDE
QOR_HUMAN_308 17 308 324 VAEAHENIIHGSGATGK PRIDE
QOR_HUMAN_61 27 61 87 KPLLPYTPGSDVAGVIEAVGDNASAFK PRIDE
QOR_HUMAN_61 28 61 88 KPLLPYTPGSDVAGVIEAVGDNASAFKK PRIDE
QOR_HUMAN_62 27 62 88 KPLLPYTPGSDVAGVIEAVGDNASAFK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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