AutismKB 2.0

Annotation Detail for LDLRAD3


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Basic Information Top
Gene Symbol:LDLRAD3 ( - )
Gene Full Name: low density lipoprotein receptor class A domain containing 3
Band: 11p13
Quick LinksEntrez ID:143458; OMIM: NA; Uniprot ID:LRAD3_HUMAN; ENSEMBL ID: ENSG00000179241; HGNC ID: 27046
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus8 / 56401214
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult6 / 19391213
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal10 / 33603072
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain2 / 11009891
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye1 / 2110544
heart1 / 8962611
intestine0 / 2344720 
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung4 / 33697411
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach0 / 966190 
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1389_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.8 ± 0.96
Basal Forebrain2.72 ± 0.54
Basal Part of Pons2.09 ± 0.35
Cerebellar Cortex3.19 ± 0.36
Cerebellar Nuclei2.82 ± 0.73
Claustrum3.14 ± 0.72
Epithalamus2.42 ± 0.88
Frontal Lobe2.51 ± 0.79
Globus Pallidus3.15 ± 0.87
Hypothalamus2.38 ± 0.72
Insula2.4 ± 0.75
Limbic Lobe2.42 ± 0.71
Mesencephalon2.71 ± 0.65
Myelencephalon2.55 ± 0.74
Occipital Lobe2.47 ± 0.64
Parietal Lobe2.34 ± 0.74
Pontine Tegmentum2.64 ± 0.77
Striatum2.47 ± 0.84
Subthalamus2.75 ± 0.78
Temporal Lobe2.32 ± 0.71
Thalamus2.51 ± 0.57
White Matter4.18 ± 0.53
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ldlrad3CBCerebellum3.07
3.27
Ldlrad3CTXCerebral cortex0.62
0.78
Ldlrad3HIPHippocampal region0.16
0.21
Ldlrad3HPFHippocampal formation0.19
0.21
Ldlrad3HYHypothalamus0.05
0.05
Ldlrad3LSXLateral septal complex0
0
Ldlrad3MBMidbrain0.23
0.41
Ldlrad3MYMedulla0.43
0.38
Ldlrad3OLFOlfactory bulb1.73
1.79
Ldlrad3PPons0.29
0.35
Ldlrad3PALPallidum0.29
0.31
Ldlrad3RHPRetrohippocampal region0.21
0.18
Ldlrad3sAMYStriatum-like amygdalar nuclei0.1
0.09
Ldlrad3STRStriatum0.3
0.32
Ldlrad3STRdStriatum dorsal region0.29
0.35
Ldlrad3STRvStriatum ventral region0.66
0.53
Ldlrad3THThalamus0.19
0.24
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018