Annotation Detail for SESN3
Basic Information Top
| Gene Symbol: | SESN3 ( MGC29667,SEST3 ) |
|---|---|
| Gene Full Name: | sestrin 3 |
| Band: | 11q21 |
| Quick Links | Entrez ID:143686; OMIM: 607768; Uniprot ID:SESN3_HUMAN; ENSEMBL ID: ENSG00000149212; HGNC ID: 23060 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.659934
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 5 / 564012 | 8 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 11 / 1939121 | 5 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 2 / 263845 | 7 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 1 / 103127 | 9 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 2 / 97250 | 20 | |
| normal | 78 / 3360307 | 23 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 3 / 125191 | 23 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 1 / 29757 | 33 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 1 / 1100989 | 0 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 1 / 149255 | 6 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 2 / 215722 | 9 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 5 / 89626 | 55 |  |
| intestine | 0 / 234472 | 0 | |
| kidney | 1 / 211777 | 4 | |
| larynx | 0 / 24145 | 0 | |
| liver | 1 / 207743 | 4 | |
| lung | 1 / 336974 | 2 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 3 / 153271 | 19 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 2 / 280825 | 7 | |
| prostate | 3 / 189345 | 15 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 0 / 96619 | 0 | |
| testis | 61 / 330442 | 184 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 3 / 232878 | 12 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: CUST_1136_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 8.47 ± 0.25 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 8.14 ± 0.17 | |
| Basal Part of Pons | 7.8 ± 0.4 | |
| Cerebellar Cortex | 7.65 ± 0.18 | |
| Cerebellar Nuclei | 7.88 ± 0.33 | |
| Claustrum | 8.36 ± 0.45 | |
| Epithalamus | 7.83 ± 0.49 | |
| Frontal Lobe | 7.9 ± 0.38 | |
| Globus Pallidus | 8.37 ± 0.21 | |
| Hypothalamus | 8.05 ± 0.38 | |
| Insula | 8.19 ± 0.29 | |
| Limbic Lobe | 7.86 ± 0.35 | |
| Mesencephalon | 8.2 ± 0.41 | |
| Myelencephalon | 8.05 ± 0.42 | |
| Occipital Lobe | 8.3 ± 0.38 | |
| Parietal Lobe | 8.04 ± 0.31 | |
| Pontine Tegmentum | 8.17 ± 0.36 | |
| Striatum | 8.87 ± 0.36 | |
| Subthalamus | 7.83 ± 0.23 | |
| Temporal Lobe | 8.02 ± 0.33 | |
| Thalamus | 8.48 ± 0.41 | |
| White Matter | 7.03 ± 0.1 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Sesn3 | CB | Cerebellum | 38.52 | |
| 90.45 | | |||
| Sesn3 | CTX | Cerebral cortex | 100 | |
| 100 | | |||
| Sesn3 | HIP | Hippocampal region | 52.34 | |
| 68.08 | | |||
| Sesn3 | HPF | Hippocampal formation | 76.95 | |
| 91.13 | | |||
| Sesn3 | HY | Hypothalamus | 100 | |
| 100 | | |||
| Sesn3 | LSX | Lateral septal complex | 100 | |
| 100 | | |||
| Sesn3 | MB | Midbrain | 100 | |
| 100 | | |||
| Sesn3 | MY | Medulla | 90.65 | |
| 100 | | |||
| Sesn3 | OLF | Olfactory bulb | 100 | |
| 100 | | |||
| Sesn3 | P | Pons | 80.73 | |
| 100 | | |||
| Sesn3 | PAL | Pallidum | 100 | |
| 100 | | |||
| Sesn3 | RHP | Retrohippocampal region | 100 | |
| 100 | | |||
| Sesn3 | sAMY | Striatum-like amygdalar nuclei | 100 | |
| 100 | | |||
| Sesn3 | STR | Striatum | 100 | |
| 100 | | |||
| Sesn3 | STRd | Striatum dorsal region | 100 | |
| 100 | | |||
| Sesn3 | STRv | Striatum ventral region | 100 | |
| 100 | | |||
| Sesn3 | TH | Thalamus | 90.46 | |
| 86.81 | |