AutismKB 2.0

Annotation Detail for PIWIL4


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Basic Information Top
Gene Symbol:PIWIL4 ( DKFZp686P01248,FLJ36156,HIWI2,MIWI2 )
Gene Full Name: piwi-like 4 (Drosophila)
Band: 11q21
Quick LinksEntrez ID:143689; OMIM: 610315; Uniprot ID:PIWL4_HUMAN; ENSEMBL ID: ENSG00000134627; HGNC ID: 18444
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult38 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal27 / 33603078
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor26 / 125191207
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone0 / 716550 
bone marrow0 / 488010 
brain4 / 11009893
cervix0 / 481710 
connective tissue26 / 149255174
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye3 / 21105414
heart1 / 8962611
intestine4 / 23447217
kidney0 / 2117770 
larynx0 / 241450 
liver1 / 2077434
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve2 / 15768126
ovary1 / 1020519
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate0 / 1893450 
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis41 / 330442124
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11191_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.03 ± 1.02
Basal Forebrain3.19 ± 0.94
Basal Part of Pons2.65 ± 0.72
Cerebellar Cortex3.17 ± 0.59
Cerebellar Nuclei2.99 ± 0.53
Claustrum3.18 ± 0.69
Epithalamus3.14 ± 0.68
Frontal Lobe2.71 ± 0.76
Globus Pallidus3.09 ± 0.95
Hypothalamus2.99 ± 0.61
Insula2.76 ± 0.48
Limbic Lobe2.91 ± 0.72
Mesencephalon3.02 ± 0.73
Myelencephalon2.96 ± 0.69
Occipital Lobe3.03 ± 0.49
Parietal Lobe2.94 ± 0.79
Pontine Tegmentum3.01 ± 0.75
Striatum3.31 ± 0.74
Subthalamus3.46 ± 0.42
Temporal Lobe2.91 ± 0.71
Thalamus2.72 ± 0.66
White Matter4.01 ± 0.46
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Piwil4CBCerebellum8.45
10.84
Piwil4CTXCerebral cortex1.14
1.14
Piwil4HIPHippocampal region1.23
1.74
Piwil4HPFHippocampal formation1.22
1.57
Piwil4HYHypothalamus0.44
0.52
Piwil4LSXLateral septal complex0.38
0.3
Piwil4MBMidbrain0.79
1.56
Piwil4MYMedulla4.33
6.04
Piwil4OLFOlfactory bulb1.49
1.23
Piwil4PPons1.25
1.79
Piwil4PALPallidum0.31
0.25
Piwil4RHPRetrohippocampal region1.13
1.16
Piwil4sAMYStriatum-like amygdalar nuclei0.89
0.98
Piwil4STRStriatum0.67
0.66
Piwil4STRdStriatum dorsal region0.7
0.73
Piwil4STRvStriatum ventral region0.58
0.45
Piwil4THThalamus0.74
1.18
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018