AutismKB 2.0

Annotation Detail for ARHGAP42


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ARHGAP42 ( FLJ32810,GRAF3,KIAA0621 )
Gene Full Name: Rho GTPase activating protein 42
Band: 11q22.1
Quick LinksEntrez ID:143872; OMIM: NA; Uniprot ID:RHG42_HUMAN; ENSEMBL ID: ENSG00000165895; HGNC ID: 26545
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus11 / 56401219
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult13 / 19391216
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal39 / 336030711
ovarian tumor3 / 7668239
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain3 / 11009892
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine5 / 23447221
kidney1 / 2117774
larynx0 / 241450 
liver1 / 2077434
lung2 / 3369745
lymph0 / 442700 
lymph node1 / 9161010
mammary gland2 / 15327113
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate0 / 1893450 
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach1 / 9661910
testis8 / 33044224
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_935_PI416573500
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.33 ± 0.51
Basal Forebrain5.97 ± 0.27
Basal Part of Pons4.55 ± 0.46
Cerebellar Cortex4.86 ± 0.39
Cerebellar Nuclei5.43 ± 0.45
Claustrum5.05 ± 0.47
Epithalamus5.86 ± 0.43
Frontal Lobe5.39 ± 0.55
Globus Pallidus6.73 ± 0.47
Hypothalamus5.73 ± 0.33
Insula5.54 ± 0.46
Limbic Lobe5.34 ± 0.68
Mesencephalon5.75 ± 0.53
Myelencephalon5.54 ± 0.62
Occipital Lobe5.65 ± 0.48
Parietal Lobe5.38 ± 0.54
Pontine Tegmentum5.63 ± 0.41
Striatum5.98 ± 0.42
Subthalamus5.41 ± 0.59
Temporal Lobe5.31 ± 0.45
Thalamus5.7 ± 0.49
White Matter5.02 ± 0.39
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
9030420J04RikCBCerebellum2.7
3.74
9030420J04RikCTXCerebral cortex1.5
1.22
9030420J04RikHIPHippocampal region0.29
0.31
9030420J04RikHPFHippocampal formation0.4
0.36
9030420J04RikHYHypothalamus0.21
0.22
9030420J04RikLSXLateral septal complex0.12
0.13
9030420J04RikMBMidbrain0.88
1.15
9030420J04RikMYMedulla4.54
5.76
9030420J04RikOLFOlfactory bulb1.4
1.71
9030420J04RikPPons0.91
0.97
9030420J04RikPALPallidum0.08
0.06
9030420J04RikRHPRetrohippocampal region0.65
0.49
9030420J04RiksAMYStriatum-like amygdalar nuclei0.84
0.78
9030420J04RikSTRStriatum0.38
0.49
9030420J04RikSTRdStriatum dorsal region0.23
0.38
9030420J04RikSTRvStriatum ventral region0.16
0.19
9030420J04RikTHThalamus1.73
1.35
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018