AutismKB 2.0

Annotation Detail for CSF2RB


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Basic Information Top
Gene Symbol:CSF2RB ( CD131,CDw131,IL3RB,IL5RB )
Gene Full Name: colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
Band: 22q12.3
Quick LinksEntrez ID:1439; OMIM: 138981; Uniprot ID:IL3RB_HUMAN; ENSEMBL ID: ENSG00000100368; HGNC ID: 2436
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus6 / 56401210
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult57 / 193912129
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia5 / 9584252
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal76 / 336030722
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone2 / 7165527
bone marrow5 / 48801102
brain2 / 11009891
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine4 / 23447217
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node10 / 91610109
mammary gland0 / 1532710 
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta39 / 280825138
prostate0 / 1893450 
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205159_at
Cell line Expression level Expression bar
721_B_lymphoblasts29.85
Adipocyte3.8
AdrenalCortex4.1
Adrenalgland3.25
Amygdala4.05
Appendix3.85
AtrioventricularNode3
BDCA4+_DentriticCells814.5
Bonemarrow47.7
BronchialEpithelialCells3.85
CD105+_Endothelial7.15
CD14+_Monocytes216.95
CD19+_BCells(neg._sel.)44.65
CD33+_Myeloid278.85
CD34+382.45
CD4+_Tcells4.15
CD56+_NKCells15.85
CD71+_EarlyErythroid3.55
CD8+_Tcells3.7
CardiacMyocytes5.45
Caudatenucleus3.45
Cerebellum3.1
CerebellumPeduncles4.35
CiliaryGanglion2.75
CingulateCortex3.9
Colorectaladenocarcinoma3.85
DorsalRootGanglion2.95
FetalThyroid3.75
Fetalbrain3.85
Fetalliver3.3
Fetallung3.9
GlobusPallidus2.8
Heart4.9
Hypothalamus4.15
Kidney3.05
Leukemia_chronicMyelogenousK-5623.5
Leukemia_promyelocytic-HL-604.65
Leukemialymphoblastic(MOLT-4)3.15
Liver5
Lung4.35
Lymphnode133.65
Lymphoma_burkitts(Daudi)10.55
Lymphoma_burkitts(Raji)5.4
MedullaOblongata3.5
OccipitalLobe3.45
OlfactoryBulb3.05
Ovary2.65
Pancreas3.1
PancreaticIslet4.1
ParietalLobe4.05
Pituitary4.55
Placenta811.05
Pons3.6
PrefrontalCortex4.7
Prostate4.6
Salivarygland3.1
SkeletalMuscle4.45
Skin2.95
SmoothMuscle4.45
Spinalcord4.15
SubthalamicNucleus3.45
SuperiorCervicalGanglion4.65
TemporalLobe3.5
Testis3.3
TestisGermCell3.25
TestisIntersitial3.25
TestisLeydigCell3.75
TestisSeminiferousTubule3.3
Thalamus3.9
Thymus5.45
Thyroid4.85
Tongue3.7
Tonsil167.2
Trachea3.2
TrigeminalGanglion3.9
Uterus3.2
UterusCorpus3.45
WholeBlood2069.35
Wholebrain3.25
colon3.9
pineal_day5.3
pineal_night4.72
retina5.25
small_intestine5.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14402_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.8 ± 1.12
Basal Forebrain2.17 ± 0.24
Basal Part of Pons1.94 ± 0.39
Cerebellar Cortex2.01 ± 0.6
Cerebellar Nuclei2.56 ± 0.7
Claustrum3.08 ± 0.91
Epithalamus2.12 ± 0.81
Frontal Lobe2.1 ± 0.67
Globus Pallidus2.99 ± 0.52
Hypothalamus2.3 ± 0.71
Insula2.59 ± 1.61
Limbic Lobe2.28 ± 0.78
Mesencephalon2.48 ± 0.81
Myelencephalon2.3 ± 0.69
Occipital Lobe2.14 ± 0.52
Parietal Lobe2.38 ± 0.83
Pontine Tegmentum2.28 ± 0.69
Striatum2.41 ± 0.5
Subthalamus2.81 ± 0.37
Temporal Lobe2.21 ± 0.73
Thalamus2.28 ± 0.74
White Matter3.06 ± 0.89
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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