AutismKB 2.0

Annotation Detail for E2F7


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Basic Information Top
Gene Symbol:E2F7 ( FLJ12981 )
Gene Full Name: E2F transcription factor 7
Band: 12q21.2
Quick LinksEntrez ID:144455; OMIM: 612046; Uniprot ID:E2F7_HUMAN; ENSEMBL ID: ENSG00000165891; HGNC ID: 23820
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst3 / 6231948
fetus7 / 56401212
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult18 / 19391219
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor11 / 26384541
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal27 / 33603078
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer2 / 10268019
retinoblastoma2 / 4635643
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow2 / 4880140
brain3 / 11009892
cervix3 / 4817162
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine3 / 23447212
kidney0 / 2117770 
larynx0 / 241450 
liver2 / 2077439
lung2 / 3369745
lymph0 / 442700 
lymph node1 / 9161010
mammary gland3 / 15327119
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate3 / 18934515
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach1 / 9661910
testis8 / 33044224
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13875_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.2 ± 1
Basal Forebrain1.89 ± 0.51
Basal Part of Pons1.56 ± 0.39
Cerebellar Cortex1.65 ± 0.68
Cerebellar Nuclei2.13 ± 0.76
Claustrum2.66 ± 0.86
Epithalamus1.52 ± 0.62
Frontal Lobe1.61 ± 0.62
Globus Pallidus2.34 ± 0.31
Hypothalamus2.04 ± 1.04
Insula1.69 ± 0.56
Limbic Lobe1.82 ± 0.62
Mesencephalon1.92 ± 0.68
Myelencephalon1.78 ± 0.61
Occipital Lobe1.94 ± 0.58
Parietal Lobe1.8 ± 0.68
Pontine Tegmentum1.88 ± 0.82
Striatum1.98 ± 0.57
Subthalamus1.9 ± 0.61
Temporal Lobe1.67 ± 0.61
Thalamus1.76 ± 0.58
White Matter2.35 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
E2f7CBCerebellum14.54
17.1
E2f7CTXCerebral cortex9.26
7.26
E2f7HIPHippocampal region6.02
5.49
E2f7HPFHippocampal formation6.2
4.97
E2f7HYHypothalamus1
0.9
E2f7LSXLateral septal complex0.88
0.67
E2f7MBMidbrain0.73
0.68
E2f7MYMedulla3.89
3.64
E2f7OLFOlfactory bulb18.18
14.71
E2f7PPons1.96
1.89
E2f7PALPallidum2.56
1.96
E2f7RHPRetrohippocampal region6.49
4.2
E2f7sAMYStriatum-like amygdalar nuclei4.05
2.69
E2f7STRStriatum8.76
6.07
E2f7STRdStriatum dorsal region11.22
7.95
E2f7STRvStriatum ventral region8.16
5.22
E2f7THThalamus1.8
1.46
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018