AutismKB 2.0

Annotation Detail for FBXL14


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Basic Information Top
Gene Symbol:FBXL14 ( Fbl14,MGC40195 )
Gene Full Name: F-box and leucine-rich repeat protein 14
Band: 12p13.33
Quick LinksEntrez ID:144699; OMIM: 609081; Uniprot ID:FXL14_HUMAN; ENSEMBL ID: ENSG00000171823; HGNC ID: 28624
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus18 / 56401231
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult51 / 193912126
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor10 / 26384537
glioma1 / 1068839
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma7 / 7175597
non-neoplasia1 / 9725010
normal76 / 336030722
ovarian tumor3 / 7668239
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone1 / 7165513
bone marrow2 / 4880140
brain8 / 11009897
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye10 / 21105447
heart0 / 896260 
intestine5 / 23447221
kidney8 / 21177737
larynx0 / 241450 
liver0 / 2077430 
lung9 / 33697426
lymph2 / 4427045
lymph node2 / 9161021
mammary gland2 / 15327113
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary3 / 10205129
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta5 / 28082517
prostate0 / 1893450 
salivary gland0 / 201550 
skin5 / 21057423
spleen1 / 5395218
stomach3 / 9661931
testis6 / 33044218
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9681_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.37 ± 0.67
Basal Forebrain7.23 ± 0.21
Basal Part of Pons7.35 ± 0.36
Cerebellar Cortex7.14 ± 0.48
Cerebellar Nuclei7.61 ± 0.41
Claustrum7.51 ± 0.44
Epithalamus6.84 ± 0.41
Frontal Lobe7.3 ± 0.53
Globus Pallidus7.36 ± 0.48
Hypothalamus7.13 ± 0.68
Insula7.18 ± 0.47
Limbic Lobe7.21 ± 0.41
Mesencephalon7.32 ± 0.49
Myelencephalon7.27 ± 0.46
Occipital Lobe7.2 ± 0.43
Parietal Lobe7.21 ± 0.42
Pontine Tegmentum7.14 ± 0.44
Striatum7.22 ± 0.42
Subthalamus7.31 ± 0.23
Temporal Lobe7.15 ± 0.46
Thalamus7.34 ± 0.36
White Matter7.18 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fbxl14CBCerebellum2.56
2.53
Fbxl14CTXCerebral cortex3.38
2.34
Fbxl14HIPHippocampal region2.54
2.22
Fbxl14HPFHippocampal formation1.87
1.62
Fbxl14HYHypothalamus0.04
0.04
Fbxl14LSXLateral septal complex0.1
0.22
Fbxl14MBMidbrain0.26
0.28
Fbxl14MYMedulla0.13
0.12
Fbxl14OLFOlfactory bulb2.45
3.81
Fbxl14PPons0.22
0.18
Fbxl14PALPallidum0.12
0.08
Fbxl14RHPRetrohippocampal region0.43
0.63
Fbxl14sAMYStriatum-like amygdalar nuclei0.19
0.11
Fbxl14STRStriatum0.23
0.18
Fbxl14STRdStriatum dorsal region0.16
0.13
Fbxl14STRvStriatum ventral region0.54
0.34
Fbxl14THThalamus1.39
1.07
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018