AutismKB 2.0

Annotation Detail for MDP1


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Basic Information Top
Gene Symbol:MDP1 ( FN6Pase,MDP-1,MGC5987 )
Gene Full Name: magnesium-dependent phosphatase 1
Band: 14q12
Quick LinksEntrez ID:145553; OMIM: NA; Uniprot ID:MGDP1_HUMAN; ENSEMBL ID: ENSG00000213920; HGNC ID: 28781
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus15 / 56401226
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult31 / 193912115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor2 / 9635920
lung tumor5 / 10312748
lymphoma2 / 7175527
non-neoplasia0 / 972500 
normal82 / 336030724
ovarian tumor0 / 766820 
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain18 / 110098916
cervix0 / 481710 
connective tissue0 / 1492550 
ear1 / 1621261
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye3 / 21105414
heart5 / 8962655
intestine3 / 23447212
kidney24 / 211777113
larynx0 / 241450 
liver2 / 2077439
lung15 / 33697444
lymph1 / 4427022
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas16 / 21481274
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate4 / 18934521
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8143_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.6 ± 0.6
Basal Forebrain7.77 ± 0.23
Basal Part of Pons8.46 ± 0.22
Cerebellar Cortex8.12 ± 0.27
Cerebellar Nuclei8.18 ± 0.44
Claustrum7.81 ± 0.67
Epithalamus8.35 ± 0.24
Frontal Lobe8.19 ± 0.34
Globus Pallidus7.81 ± 0.24
Hypothalamus8.39 ± 0.2
Insula8.23 ± 0.24
Limbic Lobe7.74 ± 0.54
Mesencephalon7.89 ± 0.4
Myelencephalon7.94 ± 0.46
Occipital Lobe7.42 ± 0.53
Parietal Lobe7.99 ± 0.37
Pontine Tegmentum7.99 ± 0.33
Striatum7.35 ± 0.33
Subthalamus8.33 ± 0.33
Temporal Lobe8.17 ± 0.33
Thalamus7.95 ± 0.37
White Matter8.01 ± 0.21
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
1810034K20RikCBCerebellum10.85
9.92
1810034K20RikCTXCerebral cortex28.85
18.65
1810034K20RikHIPHippocampal region19.97
18.61
1810034K20RikHPFHippocampal formation26.17
21.86
1810034K20RikHYHypothalamus13.9
9.42
1810034K20RikLSXLateral septal complex9.6
6.14
1810034K20RikMBMidbrain13.7
10.46
1810034K20RikMYMedulla28.89
27.15
1810034K20RikOLFOlfactory bulb30.45
20.62
1810034K20RikPPons21.09
19.2
1810034K20RikPALPallidum13.85
10.52
1810034K20RikRHPRetrohippocampal region42.88
30.94
1810034K20RiksAMYStriatum-like amygdalar nuclei19.66
12.1
1810034K20RikSTRStriatum10.39
6.62
1810034K20RikSTRdStriatum dorsal region8.37
5.46
1810034K20RikSTRvStriatum ventral region11.99
7.17
1810034K20RikTHThalamus13.08
9.14
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MGDP1_HUMAN_46 11 46 56 LYPEVPEVLKR PRIDE
MGDP1_HUMAN_57 13 57 69 LQSLGVPGAAASR PRIDE
PAp00131612 18 71 88 TSEIEGANQLLELFDLFR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018