AutismKB 2.0

Annotation Detail for GCOM1


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Basic Information Top
Gene Symbol:GCOM1 ( FLJ30973,GRINL1A,Gcom2,Gup,Gup1,Gup2,MGC126694,MGC138353,MYOZAP )
Gene Full Name: GRINL1A complex locus
Band: 15q21.3
Quick LinksEntrez ID:145781; OMIM: NA; Uniprot ID:GCOM1_HUMAN; ENSEMBL ID: ENSG00000137878; HGNC ID: 26424
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst3 / 6231948
fetus67 / 564012118
neonate2 / 3109764
infant0 / 236200 
juvenile4 / 5555671
adult142 / 193912173
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor2 / 3436658
chondrosarcoma6 / 8282372
colorectal tumor15 / 114246131
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor17 / 26384564
glioma3 / 10688328
head and neck tumor9 / 13630266
kidney tumor1 / 6895914
leukemia10 / 95842104
liver tumor10 / 96359103
lung tumor5 / 10312748
lymphoma3 / 7175541
non-neoplasia9 / 9725092
normal318 / 336030794
ovarian tumor5 / 7668265
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer11 / 102680107
retinoblastoma2 / 4635643
skin tumor4 / 12494932
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites2 / 4001549
bladder1 / 2975733
blood9 / 12347872
bone7 / 7165597
bone marrow2 / 4880140
brain110 / 110098999
cervix2 / 4817141
connective tissue11 / 14925573
ear5 / 16212308
embryonic tissue13 / 21572260
esophagus0 / 202090 
eye16 / 21105475
heart31 / 89626345
intestine23 / 23447298
kidney13 / 21177761
larynx4 / 24145165
liver15 / 20774372
lung18 / 33697453
lymph1 / 4427022
lymph node11 / 91610120
mammary gland3 / 15327119
mouth4 / 6705259
muscle4 / 10771537
nerve2 / 15768126
ovary5 / 10205148
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland2 / 16585120
placenta26 / 28082592
prostate17 / 18934589
salivary gland2 / 2015599
skin19 / 21057490
spleen3 / 5395255
stomach6 / 9661962
testis20 / 33044260
thymus5 / 8113161
thyroid0 / 474730 
tonsil0 / 169990 
trachea20 / 52413381
umbilical cord1 / 1368073
uterus34 / 232878145
vascular7 / 51780135
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212243_at
Cell line Expression level Expression bar
721_B_lymphoblasts61.45
Adipocyte19
AdrenalCortex16.5
Adrenalgland22.35
Amygdala55.05
Appendix26.95
AtrioventricularNode11.65
BDCA4+_DentriticCells88.15
Bonemarrow16.95
BronchialEpithelialCells16.35
CD105+_Endothelial28.25
CD14+_Monocytes23.95
CD19+_BCells(neg._sel.)111.35
CD33+_Myeloid25.5
CD34+25.3
CD4+_Tcells28.4
CD56+_NKCells126.1
CD71+_EarlyErythroid15.9
CD8+_Tcells19.1
CardiacMyocytes23.55
Caudatenucleus29.15
Cerebellum18.2
CerebellumPeduncles31.35
CiliaryGanglion7.55
CingulateCortex22.45
Colorectaladenocarcinoma20.45
DorsalRootGanglion14.45
FetalThyroid13.25
Fetalbrain53.05
Fetalliver16.4
Fetallung15.75
GlobusPallidus9.3
Heart19.1
Hypothalamus53.6
Kidney17.8
Leukemia_chronicMyelogenousK-56222.15
Leukemia_promyelocytic-HL-6016.5
Leukemialymphoblastic(MOLT-4)24.45
Liver25.85
Lung14.55
Lymphnode16.7
Lymphoma_burkitts(Daudi)20.9
Lymphoma_burkitts(Raji)20.8
MedullaOblongata30.95
OccipitalLobe45.15
OlfactoryBulb13.05
Ovary16.55
Pancreas14.9
PancreaticIslet12.95
ParietalLobe33.9
Pituitary18.25
Placenta18.45
Pons23.65
PrefrontalCortex34.8
Prostate26.7
Salivarygland17.5
SkeletalMuscle36.25
Skin14.85
SmoothMuscle19.25
Spinalcord24.75
SubthalamicNucleus22.5
SuperiorCervicalGanglion35.4
TemporalLobe24.15
Testis16.4
TestisGermCell20.5
TestisIntersitial15.6
TestisLeydigCell18.4
TestisSeminiferousTubule15.75
Thalamus30.95
Thymus11.7
Thyroid34.85
Tongue20.8
Tonsil18.6
Trachea23.3
TrigeminalGanglion20.25
Uterus40.05
UterusCorpus24.7
WholeBlood18.95
Wholebrain18.2
colon27.4
pineal_day59.1
pineal_night70
retina39.625
small_intestine26.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12811_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.05 ± 1.08
Basal Forebrain2.72 ± 0.61
Basal Part of Pons4.54 ± 0.28
Cerebellar Cortex3.75 ± 0.58
Cerebellar Nuclei2.84 ± 0.75
Claustrum3.72 ± 0.88
Epithalamus3.57 ± 1.06
Frontal Lobe2.48 ± 0.95
Globus Pallidus2.93 ± 1.14
Hypothalamus2.76 ± 0.87
Insula2.29 ± 0.61
Limbic Lobe2.69 ± 0.96
Mesencephalon2.57 ± 0.82
Myelencephalon2.7 ± 0.97
Occipital Lobe2.88 ± 0.85
Parietal Lobe2.51 ± 0.96
Pontine Tegmentum2.28 ± 0.69
Striatum2.14 ± 0.8
Subthalamus3.6 ± 0.6
Temporal Lobe2.49 ± 0.95
Thalamus2.51 ± 0.75
White Matter2.75 ± 0.5
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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