AutismKB 2.0

Annotation Detail for HAPLN3


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Basic Information Top
Gene Symbol:HAPLN3 ( EXLD1,HsT19883 )
Gene Full Name: hyaluronan and proteoglycan link protein 3
Band: 15q26.1
Quick LinksEntrez ID:145864; OMIM: NA; Uniprot ID:HPLN3_HUMAN; ENSEMBL ID: ENSG00000140511; HGNC ID: 21446
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst4 / 6231964
fetus8 / 56401214
neonate1 / 3109732
infant0 / 236200 
juvenile1 / 5555617
adult52 / 193912126
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor3 / 26384511
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal57 / 336030716
ovarian tumor6 / 7668278
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone3 / 7165541
bone marrow1 / 4880120
brain11 / 11009899
cervix0 / 481710 
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye1 / 2110544
heart2 / 8962622
intestine3 / 23447212
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung4 / 33697411
lymph0 / 442700 
lymph node0 / 916100 
mammary gland9 / 15327158
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary6 / 10205158
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta9 / 28082532
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen2 / 5395237
stomach1 / 9661910
testis0 / 3304420 
thymus6 / 8113173
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord1 / 1368073
uterus3 / 23287812
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_960_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.69 ± 0.88
Basal Forebrain2.34 ± 0.36
Basal Part of Pons2.48 ± 0.72
Cerebellar Cortex2.23 ± 0.8
Cerebellar Nuclei2.38 ± 0.73
Claustrum3.25 ± 1.07
Epithalamus1.82 ± 0.94
Frontal Lobe2.35 ± 0.87
Globus Pallidus2.74 ± 0.55
Hypothalamus2.34 ± 0.77
Insula1.88 ± 0.69
Limbic Lobe2.54 ± 0.83
Mesencephalon2.42 ± 0.76
Myelencephalon2.4 ± 0.86
Occipital Lobe2.11 ± 0.83
Parietal Lobe2.45 ± 0.85
Pontine Tegmentum2.38 ± 0.97
Striatum2.5 ± 0.75
Subthalamus2.49 ± 0.54
Temporal Lobe2.32 ± 0.79
Thalamus2.16 ± 0.75
White Matter2.56 ± 0.56
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Hapln3CBCerebellum2.52
2.74
Hapln3CTXCerebral cortex4.06
2.97
Hapln3HIPHippocampal region2.07
1.87
Hapln3HPFHippocampal formation2.78
2.43
Hapln3HYHypothalamus0.34
0.3
Hapln3LSXLateral septal complex0.03
0
Hapln3MBMidbrain0.91
0.89
Hapln3MYMedulla3.91
5.29
Hapln3OLFOlfactory bulb12.99
10.04
Hapln3PPons2.1
2.79
Hapln3PALPallidum1.75
1.74
Hapln3RHPRetrohippocampal region4.36
3.51
Hapln3sAMYStriatum-like amygdalar nuclei0.72
0.64
Hapln3STRStriatum1.03
0.81
Hapln3STRdStriatum dorsal region1.03
0.85
Hapln3STRvStriatum ventral region1.56
1.05
Hapln3THThalamus1.35
0.97
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018