Annotation Detail for NRG4
Basic Information Top
| Gene Symbol: | NRG4 ( DKFZp779N0541,DKFZp779N1944,HRG4 ) |
|---|---|
| Gene Full Name: | neuregulin 4 |
| Band: | 15q24.2 |
| Quick Links | Entrez ID:145957; OMIM: 610894; Uniprot ID:NRG4_HUMAN; ENSEMBL ID: ENSG00000169752; HGNC ID: 29862 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.696574
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 0 / 564012 | 0 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 |  |
| adult | 14 / 1939121 | 7 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 2 / 12794 | 156 |  |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 2 / 119369 | 16 | |
| germ cell tumor | 1 / 263845 | 3 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 5 / 136302 | 36 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 1 / 103127 | 9 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 15 / 3360307 | 4 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 3 / 125191 | 23 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 2 / 33197 | 60 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 1 / 29757 | 33 | |
| blood | 1 / 123478 | 8 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 2 / 1100989 | 1 |  |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 3 / 149255 | 20 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 1 / 211054 | 4 | |
| heart | 0 / 89626 | 0 | |
| intestine | 2 / 234472 | 8 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 0 / 24145 | 0 | |
| liver | 1 / 207743 | 4 | |
| lung | 2 / 336974 | 5 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 5 / 67052 | 74 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 2 / 189345 | 10 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 4 / 330442 | 12 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: CUST_5074_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.04 ± 1.02 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 2.71 ± 0.42 | |
| Basal Part of Pons | 2.62 ± 0.81 | |
| Cerebellar Cortex | 3.48 ± 0.45 | |
| Cerebellar Nuclei | 2.69 ± 0.67 | |
| Claustrum | 3.11 ± 0.89 | |
| Epithalamus | 3.88 ± 1.22 | |
| Frontal Lobe | 2.35 ± 0.79 | |
| Globus Pallidus | 2.13 ± 0.59 | |
| Hypothalamus | 2.99 ± 0.49 | |
| Insula | 2.27 ± 0.72 | |
| Limbic Lobe | 2.67 ± 0.94 | |
| Mesencephalon | 2.88 ± 0.83 | |
| Myelencephalon | 2.64 ± 0.88 | |
| Occipital Lobe | 3.48 ± 0.87 | |
| Parietal Lobe | 2.52 ± 0.81 | |
| Pontine Tegmentum | 2.42 ± 0.84 | |
| Striatum | 1.8 ± 0.67 | |
| Subthalamus | 2.55 ± 0.26 | |
| Temporal Lobe | 2.36 ± 0.9 | |
| Thalamus | 2.15 ± 0.74 | |
| White Matter | 2.45 ± 0.45 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Nrg4 | CB | Cerebellum | 0.53 | |
| 0.67 | | |||
| Nrg4 | CTX | Cerebral cortex | 0.79 | |
| 0.76 | | |||
| Nrg4 | HIP | Hippocampal region | 0.74 | |
| 0.82 | | |||
| Nrg4 | HPF | Hippocampal formation | 0.78 | |
| 0.77 | | |||
| Nrg4 | HY | Hypothalamus | 2.69 | |
| 2.5 | | |||
| Nrg4 | LSX | Lateral septal complex | 4 | |
| 2.59 | | |||
| Nrg4 | MB | Midbrain | 1.19 | |
| 1.48 | | |||
| Nrg4 | MY | Medulla | 4.17 | |
| 5.12 | | |||
| Nrg4 | OLF | Olfactory bulb | 4.56 | |
| 4.34 | | |||
| Nrg4 | P | Pons | 4.01 | |
| 5.58 | | |||
| Nrg4 | PAL | Pallidum | 3.57 | |
| 2.63 | | |||
| Nrg4 | RHP | Retrohippocampal region | 0.79 | |
| 0.62 | | |||
| Nrg4 | sAMY | Striatum-like amygdalar nuclei | 0.35 | |
| 0.6 | | |||
| Nrg4 | STR | Striatum | 1.17 | |
| 0.96 | | |||
| Nrg4 | STRd | Striatum dorsal region | 0.23 | |
| 0.21 | | |||
| Nrg4 | STRv | Striatum ventral region | 2.83 | |
| 2.27 | | |||
| Nrg4 | TH | Thalamus | 0.93 | |
| 0.89 | |