AutismKB 2.0

Annotation Detail for VCAN


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Basic Information Top
Gene Symbol:VCAN ( CSPG2,DKFZp686K06110,ERVR,GHAP,PG-M,WGN,WGN1 )
Gene Full Name: versican
Band: 5q14.2-q14.3
Quick LinksEntrez ID:1462; OMIM: 118661; Uniprot ID:CSPG2_HUMAN; ENSEMBL ID: ENSG00000038427; HGNC ID: 2464
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body36 / 70761508
blastocyst35 / 62319561
fetus118 / 564012209
neonate4 / 31097128
infant0 / 236200 
juvenile1 / 5555617
adult173 / 193912189
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma15 / 82823181
colorectal tumor6 / 11424652
esophageal tumor1 / 1729057
gastrointestinal tumor8 / 11936967
germ cell tumor21 / 26384579
glioma26 / 106883243
head and neck tumor18 / 136302132
kidney tumor5 / 6895972
leukemia4 / 9584241
liver tumor5 / 9635951
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia10 / 97250102
normal385 / 3360307114
ovarian tumor3 / 7668239
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood7 / 12347856
bone5 / 7165569
bone marrow4 / 4880181
brain140 / 1100989127
cervix0 / 481710 
connective tissue25 / 149255167
ear2 / 16212123
embryonic tissue98 / 215722454
esophagus1 / 2020949
eye1 / 2110544
heart17 / 89626189
intestine24 / 234472102
kidney22 / 211777103
larynx12 / 24145496
liver6 / 20774328
lung18 / 33697453
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth4 / 6705259
muscle17 / 107715157
nerve1 / 1576863
ovary6 / 10205158
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta23 / 28082581
prostate6 / 18934531
salivary gland1 / 2015549
skin12 / 21057456
spleen1 / 5395218
stomach8 / 9661982
testis17 / 33044251
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord2 / 13680146
uterus19 / 23287881
vascular38 / 51780733
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204620_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.8
Adipocyte242.2
AdrenalCortex184.7
Adrenalgland6.8
Amygdala23.6
Appendix10
AtrioventricularNode8.9
BDCA4+_DentriticCells480.7
Bonemarrow28.8
BronchialEpithelialCells29.35
CD105+_Endothelial198.75
CD14+_Monocytes2514.2
CD19+_BCells(neg._sel.)4.85
CD33+_Myeloid3920.65
CD34+15.5
CD4+_Tcells4.55
CD56+_NKCells4.95
CD71+_EarlyErythroid5.9
CD8+_Tcells4.05
CardiacMyocytes734.15
Caudatenucleus11.85
Cerebellum5.9
CerebellumPeduncles7.85
CiliaryGanglion5.15
CingulateCortex10.2
Colorectaladenocarcinoma4.6
DorsalRootGanglion6.6
FetalThyroid39.75
Fetalbrain75.4
Fetalliver6.35
Fetallung332.05
GlobusPallidus5.35
Heart8.95
Hypothalamus25.2
Kidney4.3
Leukemia_chronicMyelogenousK-5624.75
Leukemia_promyelocytic-HL-604.1
Leukemialymphoblastic(MOLT-4)3.45
Liver6.95
Lung6.75
Lymphnode5.05
Lymphoma_burkitts(Daudi)6.25
Lymphoma_burkitts(Raji)7.55
MedullaOblongata16.05
OccipitalLobe9.05
OlfactoryBulb10.4
Ovary4.35
Pancreas14.55
PancreaticIslet8.8
ParietalLobe8.1
Pituitary6.3
Placenta23.7
Pons9.85
PrefrontalCortex18.2
Prostate7.65
Salivarygland6.45
SkeletalMuscle9.9
Skin7.25
SmoothMuscle938.8
Spinalcord38.6
SubthalamicNucleus5.8
SuperiorCervicalGanglion11.65
TemporalLobe5.3
Testis3.95
TestisGermCell24.45
TestisIntersitial6
TestisLeydigCell5.95
TestisSeminiferousTubule5.95
Thalamus12.6
Thymus4.55
Thyroid9.2
Tongue12.75
Tonsil5.15
Trachea9.45
TrigeminalGanglion19.85
Uterus141
UterusCorpus48
WholeBlood789.7
Wholebrain5.65
colon12.85
pineal_day29.72
pineal_night24.74
retina35.525
small_intestine9.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P323898
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.76 ± 0.89
Basal Forebrain2.25 ± 0.3
Basal Part of Pons1.94 ± 0.51
Cerebellar Cortex2.81 ± 0.47
Cerebellar Nuclei2.47 ± 0.7
Claustrum2.85 ± 0.52
Epithalamus1.87 ± 0.85
Frontal Lobe2.26 ± 0.71
Globus Pallidus2 ± 0.87
Hypothalamus2.54 ± 0.5
Insula2.25 ± 0.8
Limbic Lobe2.29 ± 0.7
Mesencephalon2.46 ± 0.75
Myelencephalon2.37 ± 0.63
Occipital Lobe2.3 ± 0.64
Parietal Lobe2.45 ± 0.64
Pontine Tegmentum2.39 ± 0.73
Striatum2.13 ± 0.69
Subthalamus2.4 ± 0.65
Temporal Lobe2.21 ± 0.69
Thalamus2.17 ± 0.64
White Matter1.95 ± 0.37
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cspg2CBCerebellum2.44
2.05
Cspg2CTXCerebral cortex0.88
0.96
Cspg2HIPHippocampal region1.27
1.25
Cspg2HPFHippocampal formation0.91
0.91
Cspg2HYHypothalamus0.54
0.95
Cspg2LSXLateral septal complex2.61
5.85
Cspg2MBMidbrain0.53
0.52
Cspg2MYMedulla1.21
1.04
Cspg2OLFOlfactory bulb3.4
4.92
Cspg2PPons0.78
0.69
Cspg2PALPallidum0.7
0.54
Cspg2RHPRetrohippocampal region0.49
0.56
Cspg2sAMYStriatum-like amygdalar nuclei0.51
0.27
Cspg2STRStriatum1.19
1.34
Cspg2STRdStriatum dorsal region1.06
0.91
Cspg2STRvStriatum ventral region1.18
1.23
Cspg2THThalamus0.56
0.38
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CSPG2_HUMAN_1772 13 1772 1784 SFMSLTTPTQSER PRIDE
CSPG2_HUMAN_1865 29 1865 1893 EVAGTLSPHVETTFSTEPTGLVLSTVMDR PRIDE
PAp00063939 11 313 323 AQCGGGLLGVR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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