AutismKB 2.0

Annotation Detail for FBXL16


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Basic Information Top
Gene Symbol:FBXL16 ( C16orf22,FLJ33735,Fbl16,MGC33974,c380A1.1 )
Gene Full Name: F-box and leucine-rich repeat protein 16
Band: 16p13.3
Quick LinksEntrez ID:146330; OMIM: 609082; Uniprot ID:FXL16_HUMAN; ENSEMBL ID: ENSG00000127585; HGNC ID: 14150
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult57 / 193912129
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor4 / 26384515
glioma6 / 10688356
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal79 / 336030723
ovarian tumor0 / 766820 
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain74 / 110098967
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus1 / 2020949
eye7 / 21105433
heart0 / 896260 
intestine3 / 23447212
kidney2 / 2117779
larynx1 / 2414541
liver0 / 2077430 
lung16 / 33697447
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary0 / 1020510 
pancreas31 / 214812144
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta2 / 2808257
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis4 / 33044212
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_4842_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.49 ± 0.8
Basal Forebrain4.8 ± 0.23
Basal Part of Pons5.13 ± 0.9
Cerebellar Cortex4.65 ± 0.33
Cerebellar Nuclei4.28 ± 0.64
Claustrum5.43 ± 0.56
Epithalamus4.15 ± 0.59
Frontal Lobe5 ± 0.56
Globus Pallidus3.72 ± 1.01
Hypothalamus4.28 ± 0.7
Insula5.19 ± 0.43
Limbic Lobe5.33 ± 0.49
Mesencephalon4.79 ± 0.74
Myelencephalon5.01 ± 0.68
Occipital Lobe4.98 ± 0.5
Parietal Lobe5.03 ± 0.66
Pontine Tegmentum5.04 ± 0.75
Striatum6.5 ± 0.4
Subthalamus4.29 ± 0.77
Temporal Lobe5.17 ± 0.43
Thalamus4.86 ± 0.53
White Matter2.7 ± 1.1
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00075702 23 44 66 NRPCQPPPPPTLPPPSLAAPLSR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018