AutismKB 2.0

Annotation Detail for ZNF688


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Basic Information Top
Gene Symbol:ZNF688 ( - )
Gene Full Name: zinc finger protein 688
Band: 16p11.2
Quick LinksEntrez ID:146542; OMIM: NA; Uniprot ID:ZN688_HUMAN; ENSEMBL ID: ENSG00000229809; HGNC ID: 30489
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus15 / 56401226
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult28 / 193912114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor4 / 26384515
glioma6 / 10688356
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia8 / 9584283
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal58 / 336030717
ovarian tumor3 / 7668239
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain12 / 110098910
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye10 / 21105447
heart0 / 896260 
intestine8 / 23447234
kidney9 / 21177742
larynx1 / 2414541
liver1 / 2077434
lung18 / 33697453
lymph0 / 442700 
lymph node3 / 9161032
mammary gland1 / 1532716
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary3 / 10205129
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate12 / 18934563
salivary gland2 / 2015599
skin0 / 2105740 
spleen3 / 5395255
stomach0 / 966190 
testis1 / 3304423
thymus1 / 8113112
thyroid0 / 474730 
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213529_at
Cell line Expression level Expression bar
721_B_lymphoblasts22.65
Adipocyte17.75
AdrenalCortex24.55
Adrenalgland13.95
Amygdala15.95
Appendix19.1
AtrioventricularNode15.35
BDCA4+_DentriticCells21
Bonemarrow22.1
BronchialEpithelialCells16.7
CD105+_Endothelial15.35
CD14+_Monocytes18.6
CD19+_BCells(neg._sel.)18.9
CD33+_Myeloid18.75
CD34+19.65
CD4+_Tcells30.15
CD56+_NKCells21.6
CD71+_EarlyErythroid16.8
CD8+_Tcells15
CardiacMyocytes50.9
Caudatenucleus16.45
Cerebellum18.65
CerebellumPeduncles17.85
CiliaryGanglion19.9
CingulateCortex18.05
Colorectaladenocarcinoma32.15
DorsalRootGanglion13.9
FetalThyroid16.05
Fetalbrain18.25
Fetalliver19.2
Fetallung14
GlobusPallidus16.05
Heart45.7
Hypothalamus15.5
Kidney18.75
Leukemia_chronicMyelogenousK-56214.3
Leukemia_promyelocytic-HL-6013.35
Leukemialymphoblastic(MOLT-4)12.2
Liver40
Lung21.35
Lymphnode16.85
Lymphoma_burkitts(Daudi)22.35
Lymphoma_burkitts(Raji)46.1
MedullaOblongata10.5
OccipitalLobe13.45
OlfactoryBulb14.45
Ovary12.65
Pancreas14.6
PancreaticIslet27.95
ParietalLobe22.2
Pituitary21.3
Placenta11.4
Pons17.25
PrefrontalCortex18.9
Prostate17.1
Salivarygland15.6
SkeletalMuscle36.8
Skin15.3
SmoothMuscle17.8
Spinalcord16.65
SubthalamicNucleus19.55
SuperiorCervicalGanglion22.45
TemporalLobe16
Testis21.15
TestisGermCell16.85
TestisIntersitial15.6
TestisLeydigCell23.65
TestisSeminiferousTubule20.6
Thalamus17.5
Thymus8.7
Thyroid33.8
Tongue23.3
Tonsil15.7
Trachea12.45
TrigeminalGanglion17.85
Uterus11.9
UterusCorpus14.85
WholeBlood18.3
Wholebrain14.65
colon17.85
pineal_day57.94
pineal_night39.34
retina30.35
small_intestine14
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_4656_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.42 ± 0.77
Basal Forebrain4.67 ± 0.73
Basal Part of Pons4.17 ± 0.37
Cerebellar Cortex3.8 ± 0.74
Cerebellar Nuclei4.42 ± 0.8
Claustrum4.51 ± 0.97
Epithalamus3.33 ± 0.88
Frontal Lobe4.14 ± 0.84
Globus Pallidus4.99 ± 0.63
Hypothalamus3.97 ± 0.79
Insula3.96 ± 0.75
Limbic Lobe4.19 ± 0.79
Mesencephalon4.38 ± 0.74
Myelencephalon4.28 ± 0.91
Occipital Lobe4.34 ± 1.05
Parietal Lobe4.26 ± 0.77
Pontine Tegmentum4.18 ± 0.8
Striatum4.52 ± 0.83
Subthalamus3.15 ± 1.65
Temporal Lobe4.04 ± 0.88
Thalamus4.46 ± 0.72
White Matter4.22 ± 0.88
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfp688CBCerebellum3.58
3.81
Zfp688CTXCerebral cortex1.82
1.69
Zfp688HIPHippocampal region2.41
2.38
Zfp688HPFHippocampal formation1.81
1.71
Zfp688HYHypothalamus0.32
0.27
Zfp688LSXLateral septal complex0.11
0.1
Zfp688MBMidbrain0.72
0.84
Zfp688MYMedulla1.57
1.81
Zfp688OLFOlfactory bulb5.51
4.28
Zfp688PPons0.78
0.93
Zfp688PALPallidum0.21
0.19
Zfp688RHPRetrohippocampal region0.71
0.72
Zfp688sAMYStriatum-like amygdalar nuclei0.28
1.65
Zfp688STRStriatum0.8
1.22
Zfp688STRdStriatum dorsal region1.01
1.4
Zfp688STRvStriatum ventral region0.6
0.56
Zfp688THThalamus2.22
2.57
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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