AutismKB 2.0

Annotation Detail for PRSS36


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Basic Information Top
Gene Symbol:PRSS36 ( FLJ90661 )
Gene Full Name: protease, serine, 36
Band: 16p11.2
Quick LinksEntrez ID:146547; OMIM: 610560; Uniprot ID:POLS2_HUMAN; ENSEMBL ID: ENSG00000178226; HGNC ID: 26906
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult12 / 19391216
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal15 / 33603074
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain2 / 11009891
cervix5 / 48171103
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye1 / 2110544
heart1 / 8962611
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis2 / 3304426
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6129_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.61 ± 1.12
Basal Forebrain3.05 ± 0.27
Basal Part of Pons3.22 ± 0.62
Cerebellar Cortex3.32 ± 0.68
Cerebellar Nuclei3.45 ± 0.45
Claustrum4.02 ± 0.65
Epithalamus2.74 ± 0.76
Frontal Lobe3.3 ± 0.77
Globus Pallidus3.34 ± 0.71
Hypothalamus3.13 ± 0.76
Insula2.94 ± 0.6
Limbic Lobe3.38 ± 0.83
Mesencephalon3.35 ± 0.7
Myelencephalon3.36 ± 0.73
Occipital Lobe3.48 ± 0.71
Parietal Lobe3.33 ± 0.75
Pontine Tegmentum3.36 ± 0.77
Striatum2.93 ± 0.79
Subthalamus3.35 ± 0.88
Temporal Lobe3.29 ± 0.76
Thalamus3.42 ± 0.61
White Matter3.8 ± 0.49
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Prss36CBCerebellum2.02
2.17
Prss36CTXCerebral cortex1.47
1.52
Prss36HIPHippocampal region1.04
1.06
Prss36HPFHippocampal formation0.88
0.79
Prss36HYHypothalamus0.37
0.26
Prss36LSXLateral septal complex0.03
0
Prss36MBMidbrain1.08
1.13
Prss36MYMedulla1.95
2.02
Prss36OLFOlfactory bulb11.21
10.01
Prss36PPons0.99
0.98
Prss36PALPallidum0.42
0.4
Prss36RHPRetrohippocampal region0.52
0.32
Prss36sAMYStriatum-like amygdalar nuclei0.09
0.19
Prss36STRStriatum0.44
0.36
Prss36STRdStriatum dorsal region0.1
0.09
Prss36STRvStriatum ventral region2.18
1.42
Prss36THThalamus1.4
1.32
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018