AutismKB 2.0

Annotation Detail for CSRP2


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Basic Information Top
Gene Symbol:CSRP2 ( CRP2,LMO5,SmLIM )
Gene Full Name: cysteine and glycine-rich protein 2
Band: 12q21.2
Quick LinksEntrez ID:1466; OMIM: 601871; Uniprot ID:CSRP2_HUMAN; ENSEMBL ID: ENSG00000175183; HGNC ID: 2470
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst3 / 6231948
fetus54 / 56401295
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult57 / 193912129
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor9 / 26384534
glioma8 / 10688374
head and neck tumor3 / 13630222
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia5 / 9725051
normal130 / 336030738
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor11 / 12519187
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone4 / 7165555
bone marrow0 / 488010 
brain47 / 110098942
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye17 / 21105480
heart10 / 89626111
intestine2 / 2344728
kidney3 / 21177714
larynx1 / 2414541
liver3 / 20774314
lung5 / 33697414
lymph0 / 442700 
lymph node1 / 9161010
mammary gland3 / 15327119
mouth1 / 6705214
muscle5 / 10771546
nerve1 / 1576863
ovary1 / 1020519
pancreas2 / 2148129
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta10 / 28082535
prostate0 / 1893450 
salivary gland1 / 2015549
skin5 / 21057423
spleen2 / 5395237
stomach2 / 9661920
testis8 / 33044224
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord2 / 13680146
uterus11 / 23287847
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211126_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts21.15
Adipocyte27.75
AdrenalCortex26.8
Adrenalgland17.4
Amygdala44.4
Appendix83.05
AtrioventricularNode22.5
BDCA4+_DentriticCells20.15
Bonemarrow23.95
BronchialEpithelialCells141.95
CD105+_Endothelial19.9
CD14+_Monocytes21.25
CD19+_BCells(neg._sel.)20.5
CD33+_Myeloid24.65
CD34+21.3
CD4+_Tcells20.65
CD56+_NKCells14.45
CD71+_EarlyErythroid19.7
CD8+_Tcells17.35
CardiacMyocytes75.05
Caudatenucleus38
Cerebellum17.75
CerebellumPeduncles47.15
CiliaryGanglion39
CingulateCortex35.75
Colorectaladenocarcinoma35.4
DorsalRootGanglion21.4
FetalThyroid123.65
Fetalbrain838.7
Fetalliver17.2
Fetallung41.1
GlobusPallidus17.7
Heart35.25
Hypothalamus84.9
Kidney61.7
Leukemia_chronicMyelogenousK-56217.65
Leukemia_promyelocytic-HL-6015.1
Leukemialymphoblastic(MOLT-4)14.75
Liver37.75
Lung61.1
Lymphnode58.7
Lymphoma_burkitts(Daudi)26.15
Lymphoma_burkitts(Raji)28.75
MedullaOblongata18
OccipitalLobe30.4
OlfactoryBulb29.65
Ovary27.8
Pancreas33.25
PancreaticIslet44.9
ParietalLobe45.15
Pituitary35.95
Placenta140.65
Pons34.95
PrefrontalCortex47.35
Prostate83.95
Salivarygland25.15
SkeletalMuscle46.2
Skin21.95
SmoothMuscle29.35
Spinalcord37.7
SubthalamicNucleus22.75
SuperiorCervicalGanglion28.55
TemporalLobe29.4
Testis54.4
TestisGermCell45.75
TestisIntersitial52.95
TestisLeydigCell56.15
TestisSeminiferousTubule40.85
Thalamus37.4
Thymus40.95
Thyroid176.1
Tongue70.6
Tonsil46.95
Trachea47.55
TrigeminalGanglion34.55
Uterus84.8
UterusCorpus58.8
WholeBlood14.1
Wholebrain46.05
colon33.35
pineal_day41.62
pineal_night31.16
retina738.9
small_intestine54.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P44724
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.49 ± 0.36
Basal Forebrain8.86 ± 0.17
Basal Part of Pons8.94 ± 0.37
Cerebellar Cortex8.76 ± 0.41
Cerebellar Nuclei9.52 ± 0.45
Claustrum8.58 ± 0.51
Epithalamus10.27 ± 0.67
Frontal Lobe9.09 ± 0.47
Globus Pallidus10.31 ± 0.54
Hypothalamus9.34 ± 0.58
Insula9.05 ± 0.32
Limbic Lobe8.62 ± 0.54
Mesencephalon8.81 ± 0.44
Myelencephalon9.1 ± 0.52
Occipital Lobe8.74 ± 0.4
Parietal Lobe8.77 ± 0.47
Pontine Tegmentum9.1 ± 0.52
Striatum9.46 ± 0.56
Subthalamus10.02 ± 0.13
Temporal Lobe8.75 ± 0.39
Thalamus9.14 ± 0.44
White Matter9.03 ± 0.97
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Csrp2CBCerebellum1.34
2.77
Csrp2CTXCerebral cortex0.69
0.94
Csrp2HIPHippocampal region1.24
1.86
Csrp2HPFHippocampal formation0.87
1.34
Csrp2HYHypothalamus0.26
1.14
Csrp2LSXLateral septal complex2.03
2.09
Csrp2MBMidbrain0.41
0.87
Csrp2MYMedulla1.34
3.06
Csrp2OLFOlfactory bulb0.58
0.62
Csrp2PPons1.57
2.33
Csrp2PALPallidum0.18
0.21
Csrp2RHPRetrohippocampal region0.34
0.73
Csrp2sAMYStriatum-like amygdalar nuclei0.73
0.47
Csrp2STRStriatum0.51
0.48
Csrp2STRdStriatum dorsal region0.27
0.31
Csrp2STRvStriatum ventral region0.61
0.47
Csrp2THThalamus0.71
0.99
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CSRP2_HUMAN_15 13 15 27 TVYHAEEVQCDGR PRIDE
CSRP2_HUMAN_151 10 151 160 SLESTTLTEK PRIDE
CSRP2_HUMAN_69 15 69 83 GYGYGQGAGTLNMDR PRIDE
CSRP2_HUMAN_87 21 87 107 LGIKPESVQPHRPTTNPNTSK PRIDE
PAp00004498 18 42 59 KNLDSTTVAIHDEEIYCK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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