AutismKB 2.0

Annotation Detail for RTN4RL1


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Basic Information Top
Gene Symbol:RTN4RL1 ( DKFZp547J144,NGRH2,NgR3 )
Gene Full Name: reticulon 4 receptor-like 1
Band: 17p13.3
Quick LinksEntrez ID:146760; OMIM: 610461; Uniprot ID:R4RL1_HUMAN; ENSEMBL ID: ENSG00000185924; HGNC ID: 21329
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult13 / 19391216
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal19 / 33603075
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone3 / 7165541
bone marrow0 / 488010 
brain4 / 11009893
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye7 / 21105433
heart0 / 896260 
intestine1 / 2344724
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung7 / 33697420
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P66481
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.88 ± 1.18
Basal Forebrain4.3 ± 0.67
Basal Part of Pons5.04 ± 0.36
Cerebellar Cortex5.97 ± 0.36
Cerebellar Nuclei4.78 ± 0.79
Claustrum5.95 ± 0.93
Epithalamus5.14 ± 0.79
Frontal Lobe6.25 ± 0.7
Globus Pallidus3.22 ± 1.06
Hypothalamus4.51 ± 0.43
Insula6.43 ± 0.28
Limbic Lobe6.37 ± 1.13
Mesencephalon5.29 ± 0.96
Myelencephalon5.6 ± 0.75
Occipital Lobe4.76 ± 1.28
Parietal Lobe5.95 ± 0.75
Pontine Tegmentum5.68 ± 0.9
Striatum3.93 ± 1.27
Subthalamus4.54 ± 0.75
Temporal Lobe6.42 ± 0.74
Thalamus5.81 ± 0.68
White Matter2.99 ± 0.52
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rtn4rl1CBCerebellum46.29
34.99
Rtn4rl1CTXCerebral cortex99.55
89.83
Rtn4rl1HIPHippocampal region82.17
100
Rtn4rl1HPFHippocampal formation80.22
100
Rtn4rl1HYHypothalamus16.78
12.18
Rtn4rl1LSXLateral septal complex34
24.87
Rtn4rl1MBMidbrain12.44
9.7
Rtn4rl1MYMedulla12.21
9.63
Rtn4rl1OLFOlfactory bulb84.47
69.76
Rtn4rl1PPons13.27
10.43
Rtn4rl1PALPallidum13.11
8.97
Rtn4rl1RHPRetrohippocampal region77.64
73.21
Rtn4rl1sAMYStriatum-like amygdalar nuclei21.2
15.17
Rtn4rl1STRStriatum43.42
28.14
Rtn4rl1STRdStriatum dorsal region43.14
27.4
Rtn4rl1STRvStriatum ventral region65.81
40.9
Rtn4rl1THThalamus55.42
51.61
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018