AutismKB 2.0

Annotation Detail for TMEM199


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TMEM199 ( C17orf32,MGC45714 )
Gene Full Name: transmembrane protein 199
Band: 17q11.2
Quick LinksEntrez ID:147007; OMIM: NA; Uniprot ID:TM199_HUMAN; ENSEMBL ID: ENSG00000004139,ENSG00000244045; HGNC ID: 18085
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus34 / 56401260
neonate1 / 3109732
infant1 / 2362042
juvenile0 / 555560 
adult69 / 193912135
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor6 / 26384522
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor3 / 6895943
leukemia4 / 9584241
liver tumor4 / 9635941
lung tumor0 / 1031270 
lymphoma3 / 7175541
non-neoplasia3 / 9725030
normal140 / 336030741
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer6 / 10268058
retinoblastoma1 / 4635621
skin tumor4 / 12494932
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood6 / 12347848
bone1 / 7165513
bone marrow0 / 488010 
brain34 / 110098930
cervix1 / 4817120
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye4 / 21105418
heart4 / 8962644
intestine8 / 23447234
kidney10 / 21177747
larynx0 / 241450 
liver9 / 20774343
lung18 / 33697453
lymph0 / 442700 
lymph node4 / 9161043
mammary gland11 / 15327171
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary1 / 1020519
pancreas3 / 21481213
parathyroid4 / 20539194
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta11 / 28082539
prostate12 / 18934563
salivary gland0 / 201550 
skin7 / 21057433
spleen2 / 5395237
stomach6 / 9661962
testis6 / 33044218
thymus3 / 8113136
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P56884
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.89 ± 0.78
Basal Forebrain4.53 ± 0.19
Basal Part of Pons4.92 ± 0.34
Cerebellar Cortex4.93 ± 0.36
Cerebellar Nuclei4.78 ± 0.37
Claustrum4.62 ± 0.78
Epithalamus4.54 ± 0.46
Frontal Lobe4.71 ± 0.44
Globus Pallidus4.69 ± 0.64
Hypothalamus4.79 ± 0.48
Insula4.79 ± 0.38
Limbic Lobe4.79 ± 0.46
Mesencephalon4.69 ± 0.42
Myelencephalon4.65 ± 0.53
Occipital Lobe4.71 ± 0.45
Parietal Lobe4.69 ± 0.52
Pontine Tegmentum4.8 ± 0.55
Striatum4.56 ± 0.48
Subthalamus4.74 ± 0.15
Temporal Lobe4.74 ± 0.45
Thalamus4.62 ± 0.49
White Matter4.83 ± 0.98
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
AI316787CBCerebellum15.6
17.71
AI316787CTXCerebral cortex28.33
21.18
AI316787HIPHippocampal region19.32
19.61
AI316787HPFHippocampal formation25.55
24.93
AI316787HYHypothalamus5.4
4.47
AI316787LSXLateral septal complex8.15
5.92
AI316787MBMidbrain20.63
19.4
AI316787MYMedulla14.87
17.93
AI316787OLFOlfactory bulb15.78
11.47
AI316787PPons14.7
17.1
AI316787PALPallidum9.33
10.93
AI316787RHPRetrohippocampal region34.02
30.34
AI316787sAMYStriatum-like amygdalar nuclei7.33
4.87
AI316787STRStriatum6.5
4.55
AI316787STRdStriatum dorsal region6.2
4.57
AI316787STRvStriatum ventral region7.25
4.32
AI316787THThalamus13.28
12
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00005269 11 30 40 LRAELEAALGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018