AutismKB 2.0

Annotation Detail for CST3


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Basic Information Top
Gene Symbol:CST3 ( ARMD11,MGC117328 )
Gene Full Name: cystatin C
Band: 20p11.21
Quick LinksEntrez ID:1471; OMIM: 604312; Uniprot ID:CYTC_HUMAN; ENSEMBL ID: ENSG00000101439; HGNC ID: 2475
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus57 / 564012101
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult444 / 1939121228
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma1 / 1747557
breast (mammary gland) tumor5 / 9417853
cervical tumor3 / 3436687
chondrosarcoma17 / 82823205
colorectal tumor11 / 11424696
esophageal tumor2 / 17290115
gastrointestinal tumor22 / 119369184
germ cell tumor12 / 26384545
glioma211 / 1068831974
head and neck tumor6 / 13630244
kidney tumor14 / 68959203
leukemia0 / 958420 
liver tumor28 / 96359290
lung tumor11 / 103127106
lymphoma5 / 7175569
non-neoplasia21 / 97250215
normal531 / 3360307158
ovarian tumor37 / 76682482
pancreatic tumor39 / 104616372
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer28 / 102680272
retinoblastoma0 / 463560 
skin tumor24 / 124949192
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor19 / 90257210
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue7 / 13106534
adrenal gland3 / 3319790
ascites3 / 4001574
bladder2 / 2975767
blood3 / 12347824
bone25 / 71655348
bone marrow5 / 48801102
brain450 / 1100989408
cervix3 / 4817162
connective tissue23 / 149255154
ear4 / 16212246
embryonic tissue5 / 21572223
esophagus2 / 2020998
eye52 / 211054246
heart20 / 89626223
intestine40 / 234472170
kidney24 / 211777113
larynx2 / 2414582
liver35 / 207743168
lung40 / 336974118
lymph0 / 442700 
lymph node13 / 91610141
mammary gland19 / 153271123
mouth0 / 670520 
muscle19 / 107715176
nerve3 / 15768190
ovary46 / 102051450
pancreas52 / 214812242
parathyroid14 / 20539681
pharynx2 / 4132848
pituitary gland9 / 16585542
placenta21 / 28082574
prostate52 / 189345274
salivary gland3 / 20155148
skin32 / 210574151
spleen8 / 53952148
stomach43 / 96619445
testis20 / 33044260
thymus3 / 8113136
thyroid2 / 4747342
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus29 / 232878124
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201360_at
Cell line Expression level Expression bar
721_B_lymphoblasts57.15
Adipocyte2208.35
AdrenalCortex220.35
Adrenalgland286.7
Amygdala3056.4
Appendix398.8
AtrioventricularNode148.65
BDCA4+_DentriticCells1560.45
Bonemarrow38.65
BronchialEpithelialCells180.2
CD105+_Endothelial107.35
CD14+_Monocytes2694.4
CD19+_BCells(neg._sel.)48.25
CD33+_Myeloid1678.75
CD34+264.4
CD4+_Tcells12.85
CD56+_NKCells287.05
CD71+_EarlyErythroid6.15
CD8+_Tcells3.25
CardiacMyocytes184.25
Caudatenucleus1657.2
Cerebellum893
CerebellumPeduncles1209.35
CiliaryGanglion192.05
CingulateCortex1765.85
Colorectaladenocarcinoma633.3
DorsalRootGanglion223.55
FetalThyroid380.25
Fetalbrain205.45
Fetalliver52.9
Fetallung154.95
GlobusPallidus770.9
Heart1258.25
Hypothalamus990.7
Kidney139.55
Leukemia_chronicMyelogenousK-56236.3
Leukemia_promyelocytic-HL-602.55
Leukemialymphoblastic(MOLT-4)2.2
Liver761.1
Lung2035.65
Lymphnode470.05
Lymphoma_burkitts(Daudi)3.75
Lymphoma_burkitts(Raji)2.7
MedullaOblongata1514.3
OccipitalLobe2158.55
OlfactoryBulb957.1
Ovary143
Pancreas155.75
PancreaticIslet341.1
ParietalLobe1533.6
Pituitary529.05
Placenta340.7
Pons873.1
PrefrontalCortex2692
Prostate1228.9
Salivarygland558.7
SkeletalMuscle125.95
Skin106.95
SmoothMuscle194.9
Spinalcord1862.35
SubthalamicNucleus1236
SuperiorCervicalGanglion136.65
TemporalLobe1513.45
Testis502.6
TestisGermCell1672.7
TestisIntersitial492.55
TestisLeydigCell461.2
TestisSeminiferousTubule724.05
Thalamus1744.8
Thymus452
Thyroid1276.25
Tongue266.1
Tonsil111.25
Trachea447.35
TrigeminalGanglion302.2
Uterus519.75
UterusCorpus112.15
WholeBlood748.1
Wholebrain2990.65
colon335.95
pineal_day975.68
pineal_night805.78
retina3981.3
small_intestine333.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P216294
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala11.38 ± 0.35
Basal Forebrain11.5 ± 0.27
Basal Part of Pons10.57 ± 0.44
Cerebellar Cortex10.77 ± 0.2
Cerebellar Nuclei10.98 ± 0.56
Claustrum10.49 ± 0.57
Epithalamus11.69 ± 0.41
Frontal Lobe11.28 ± 0.52
Globus Pallidus11.82 ± 0.32
Hypothalamus11.16 ± 0.35
Insula11.05 ± 0.64
Limbic Lobe11.01 ± 0.53
Mesencephalon11.41 ± 0.53
Myelencephalon11.41 ± 0.44
Occipital Lobe11.57 ± 0.39
Parietal Lobe11.42 ± 0.47
Pontine Tegmentum11.3 ± 0.41
Striatum12 ± 0.45
Subthalamus10.72 ± 0.52
Temporal Lobe11.2 ± 0.41
Thalamus11.65 ± 0.49
White Matter9.65 ± 0.05
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cst3CBCerebellum99.59
100
Cst3CTXCerebral cortex100
100
Cst3HIPHippocampal region100
100
Cst3HPFHippocampal formation100
100
Cst3HYHypothalamus100
100
Cst3LSXLateral septal complex100
100
Cst3MBMidbrain100
100
Cst3MYMedulla100
100
Cst3OLFOlfactory bulb100
100
Cst3PPons100
100
Cst3PALPallidum100
100
Cst3RHPRetrohippocampal region100
100
Cst3sAMYStriatum-like amygdalar nuclei100
100
Cst3STRStriatum100
100
Cst3STRdStriatum dorsal region100
100
Cst3STRvStriatum ventral region100
100
Cst3THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CYTC_HUMAN_0 0 0 0 ALDFAVGEYNK PRIDE
CYTC_HUMAN_35 16 35 50 LVGGPMDASVEEEGVR PRIDE
PAp00028205 17 102 118 TQPNLDNCPFHDQPHLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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