AutismKB 2.0

Annotation Detail for CST5


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Basic Information Top
Gene Symbol:CST5 ( MGC71922 )
Gene Full Name: cystatin D
Band: 20p11.21
Quick LinksEntrez ID:1473; OMIM: 123858; Uniprot ID:CYTD_HUMAN; ENSEMBL ID: ENSG00000170367; HGNC ID: 2477
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult2 / 19391211
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal12 / 33603073
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland9 / 20155446
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207925_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.5
Adipocyte5.85
AdrenalCortex4.95
Adrenalgland4.4
Amygdala5.15
Appendix4.8
AtrioventricularNode3.6
BDCA4+_DentriticCells5.05
Bonemarrow4.7
BronchialEpithelialCells4.55
CD105+_Endothelial4.8
CD14+_Monocytes5.4
CD19+_BCells(neg._sel.)4.75
CD33+_Myeloid6
CD34+5.9
CD4+_Tcells5.1
CD56+_NKCells5.3
CD71+_EarlyErythroid4.5
CD8+_Tcells4.2
CardiacMyocytes6.15
Caudatenucleus4.4
Cerebellum3.95
CerebellumPeduncles7.8
CiliaryGanglion3.35
CingulateCortex5.1
Colorectaladenocarcinoma4.9
DorsalRootGanglion3.65
FetalThyroid4.7
Fetalbrain4.5
Fetalliver4.15
Fetallung3.75
GlobusPallidus4.05
Heart6.2
Hypothalamus5.35
Kidney3.9
Leukemia_chronicMyelogenousK-5624.25
Leukemia_promyelocytic-HL-604.25
Leukemialymphoblastic(MOLT-4)3.9
Liver6.35
Lung5.4
Lymphnode4.2
Lymphoma_burkitts(Daudi)6.15
Lymphoma_burkitts(Raji)6.6
MedullaOblongata4.45
OccipitalLobe4.35
OlfactoryBulb3.8
Ovary3.2
Pancreas3.8
PancreaticIslet5.15
ParietalLobe5.45
Pituitary5.65
Placenta5
Pons4.6
PrefrontalCortex6.15
Prostate5.7
Salivarygland2143.55
SkeletalMuscle5.55
Skin3.7
SmoothMuscle5.45
Spinalcord5.2
SubthalamicNucleus4.65
SuperiorCervicalGanglion5.45
TemporalLobe4.55
Testis4.2
TestisGermCell4.05
TestisIntersitial4
TestisLeydigCell4.8
TestisSeminiferousTubule4.2
Thalamus9.45
Thymus3.85
Thyroid8.25
Tongue4.7
Tonsil4.55
Trachea4.05
TrigeminalGanglion4.75
Uterus3.9
UterusCorpus4.3
WholeBlood5.35
Wholebrain5.45
colon4.85
pineal_day5.96
pineal_night5.88
retina6.2
small_intestine4.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11175_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.2 ± 1.06
Basal Forebrain1.8 ± 0.43
Basal Part of Pons1.43 ± 0.38
Cerebellar Cortex1.49 ± 0.55
Cerebellar Nuclei2.11 ± 0.79
Claustrum2.59 ± 0.89
Epithalamus1.35 ± 0.76
Frontal Lobe1.71 ± 0.74
Globus Pallidus2.48 ± 0.47
Hypothalamus1.72 ± 0.64
Insula1.53 ± 0.59
Limbic Lobe1.74 ± 0.59
Mesencephalon2.03 ± 0.76
Myelencephalon1.86 ± 0.71
Occipital Lobe1.93 ± 0.74
Parietal Lobe1.93 ± 0.71
Pontine Tegmentum1.84 ± 0.67
Striatum1.96 ± 0.69
Subthalamus1.93 ± 0.66
Temporal Lobe1.68 ± 0.69
Thalamus1.77 ± 0.62
White Matter2.23 ± 0.38
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00435313 15 98 112 SQPNLDNCPFNDQPK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018