AutismKB 2.0

Annotation Detail for APCDD1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:APCDD1 ( B7323,DRAPC1 )
Gene Full Name: adenomatosis polyposis coli down-regulated 1
Band: 18p11.22
Quick LinksEntrez ID:147495; OMIM: 607479; Uniprot ID:APCD1_HUMAN; ENSEMBL ID: ENSG00000154856; HGNC ID: 15718
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst3 / 6231948
fetus16 / 56401228
neonate1 / 3109732
infant0 / 236200 
juvenile2 / 5555635
adult78 / 193912140
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor12 / 119369100
germ cell tumor8 / 26384530
glioma9 / 10688384
head and neck tumor14 / 136302102
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal103 / 336030730
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain39 / 110098935
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye13 / 21105461
heart7 / 8962678
intestine2 / 2344728
kidney0 / 2117770 
larynx1 / 2414541
liver2 / 2077439
lung8 / 33697423
lymph0 / 442700 
lymph node2 / 9161021
mammary gland2 / 15327113
mouth6 / 6705289
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta14 / 28082549
prostate3 / 18934515
salivary gland7 / 20155347
skin7 / 21057433
spleen0 / 539520 
stomach12 / 96619124
testis3 / 3304429
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P337262
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.42 ± 0.16
Basal Forebrain8.61 ± 0.33
Basal Part of Pons7.96 ± 0.32
Cerebellar Cortex8.19 ± 0.2
Cerebellar Nuclei8.55 ± 0.28
Claustrum8.03 ± 0.37
Epithalamus9.28 ± 0.34
Frontal Lobe8.63 ± 0.37
Globus Pallidus9.01 ± 0.18
Hypothalamus9 ± 0.85
Insula8.65 ± 0.28
Limbic Lobe8.66 ± 0.44
Mesencephalon8.64 ± 0.3
Myelencephalon8.72 ± 0.44
Occipital Lobe8.72 ± 0.46
Parietal Lobe8.52 ± 0.42
Pontine Tegmentum8.75 ± 0.32
Striatum9.27 ± 0.29
Subthalamus7.91 ± 0.24
Temporal Lobe8.56 ± 0.32
Thalamus8.86 ± 0.34
White Matter8.47 ± 0.23
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018