Annotation Detail for TMC4
Basic Information Top
| Gene Symbol: | TMC4 ( MGC39329 ) |
|---|---|
| Gene Full Name: | transmembrane channel-like 4 |
| Band: | 19q13.42 |
| Quick Links | Entrez ID:147798; OMIM: NA; Uniprot ID:TMC4_HUMAN; ENSEMBL ID: ENSG00000167608; HGNC ID: 22998 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.355126
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 2 / 564012 | 3 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 71 / 1939121 | 36 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 |  |
| breast (mammary gland) tumor | 13 / 94178 | 138 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 11 / 114246 | 96 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 4 / 119369 | 33 | |
| germ cell tumor | 0 / 263845 | 0 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 1 / 95842 | 10 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 2 / 103127 | 19 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 42 / 3360307 | 12 | |
| ovarian tumor | 9 / 76682 | 117 | |
| pancreatic tumor | 2 / 104616 | 19 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 13 / 102680 | 126 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 5 / 90257 | 55 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 1 / 29757 | 33 | |
| blood | 2 / 123478 | 16 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 2 / 1100989 | 1 |  |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 1 / 215722 | 4 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 2 / 211054 | 9 | |
| heart | 0 / 89626 | 0 | |
| intestine | 15 / 234472 | 63 | |
| kidney | 7 / 211777 | 33 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 5 / 336974 | 14 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 14 / 153271 | 91 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 10 / 102051 | 97 | |
| pancreas | 3 / 214812 | 13 | |
| parathyroid | 1 / 20539 | 48 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 11 / 280825 | 39 | |
| prostate | 22 / 189345 | 116 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 1 / 210574 | 4 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 4 / 96619 | 41 | |
| testis | 0 / 330442 | 0 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 2 / 47473 | 42 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 5 / 232878 | 21 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: CUST_11377_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.24 ± 0.95 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 2.77 ± 0.4 | |
| Basal Part of Pons | 2.83 ± 0.49 | |
| Cerebellar Cortex | 2.91 ± 0.71 | |
| Cerebellar Nuclei | 3.4 ± 0.6 | |
| Claustrum | 3.45 ± 0.83 | |
| Epithalamus | 3.32 ± 0.62 | |
| Frontal Lobe | 3 ± 0.69 | |
| Globus Pallidus | 3.53 ± 0.71 | |
| Hypothalamus | 2.66 ± 0.74 | |
| Insula | 2.75 ± 0.62 | |
| Limbic Lobe | 3.15 ± 0.64 | |
| Mesencephalon | 3.04 ± 0.66 | |
| Myelencephalon | 3.16 ± 0.72 | |
| Occipital Lobe | 3.33 ± 0.62 | |
| Parietal Lobe | 3.05 ± 0.66 | |
| Pontine Tegmentum | 3.04 ± 0.63 | |
| Striatum | 3.37 ± 0.59 | |
| Subthalamus | 3.22 ± 0.43 | |
| Temporal Lobe | 3.04 ± 0.66 | |
| Thalamus | 3.15 ± 0.61 | |
| White Matter | 2.63 ± 0.86 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Tmc4 | CB | Cerebellum | 2.12 | |
| 2.28 | | |||
| Tmc4 | CTX | Cerebral cortex | 3.01 | |
| 2.03 | | |||
| Tmc4 | HIP | Hippocampal region | 1.48 | |
| 1.26 | | |||
| Tmc4 | HPF | Hippocampal formation | 1.41 | |
| 1.22 | | |||
| Tmc4 | HY | Hypothalamus | 5.73 | |
| 3.75 | | |||
| Tmc4 | LSX | Lateral septal complex | 1.24 | |
| 0.71 | | |||
| Tmc4 | MB | Midbrain | 2.58 | |
| 1.97 | | |||
| Tmc4 | MY | Medulla | 9.27 | |
| 9.2 | | |||
| Tmc4 | OLF | Olfactory bulb | 3.96 | |
| 3.04 | | |||
| Tmc4 | P | Pons | 4.21 | |
| 3.45 | | |||
| Tmc4 | PAL | Pallidum | 3.99 | |
| 4.19 | | |||
| Tmc4 | RHP | Retrohippocampal region | 1.15 | |
| 1.1 | | |||
| Tmc4 | sAMY | Striatum-like amygdalar nuclei | 9.74 | |
| 6.63 | | |||
| Tmc4 | STR | Striatum | 2.17 | |
| 1.49 | | |||
| Tmc4 | STRd | Striatum dorsal region | 1 | |
| 0.71 | | |||
| Tmc4 | STRv | Striatum ventral region | 3.79 | |
| 2.46 | | |||
| Tmc4 | TH | Thalamus | 1.27 | |
| 1.25 | |