AutismKB 2.0

Annotation Detail for CAPN12


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Basic Information Top
Gene Symbol:CAPN12 ( MGC20576 )
Gene Full Name: calpain 12
Band: 19q13.2
Quick LinksEntrez ID:147968; OMIM: 608839; Uniprot ID:CAN12_HUMAN; ENSEMBL ID: ENSG00000182472; HGNC ID: 13249
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus27 / 56401247
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult159 / 193912181
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor4 / 11424635
esophageal tumor5 / 17290289
gastrointestinal tumor7 / 11936958
germ cell tumor4 / 26384515
glioma4 / 10688337
head and neck tumor8 / 13630258
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal125 / 336030737
ovarian tumor10 / 76682130
pancreatic tumor11 / 104616105
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer53 / 102680516
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain21 / 110098919
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus5 / 20209247
eye3 / 21105414
heart3 / 8962633
intestine9 / 23447238
kidney7 / 21177733
larynx5 / 24145207
liver11 / 20774352
lung5 / 33697414
lymph0 / 442700 
lymph node5 / 9161054
mammary gland8 / 15327152
mouth2 / 6705229
muscle5 / 10771546
nerve1 / 1576863
ovary12 / 102051117
pancreas16 / 21481274
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta18 / 28082564
prostate62 / 189345327
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach7 / 9661972
testis2 / 3304426
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus13 / 23287855
vascular4 / 5178077
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P79040
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala1.88 ± 1.04
Basal Forebrain1.4 ± 0.19
Basal Part of Pons1.6 ± 0.88
Cerebellar Cortex1.35 ± 0.89
Cerebellar Nuclei1.7 ± 0.75
Claustrum2.27 ± 0.87
Epithalamus1.17 ± 0.71
Frontal Lobe1.36 ± 0.65
Globus Pallidus1.93 ± 0.35
Hypothalamus1.83 ± 0.6
Insula1.21 ± 0.38
Limbic Lobe1.56 ± 0.83
Mesencephalon1.6 ± 0.74
Myelencephalon1.51 ± 0.65
Occipital Lobe1.28 ± 0.54
Parietal Lobe1.5 ± 0.85
Pontine Tegmentum1.33 ± 0.6
Striatum1.54 ± 0.55
Subthalamus1.56 ± 0.62
Temporal Lobe1.3 ± 0.51
Thalamus1.38 ± 0.61
White Matter1.81 ± 0.02
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Capn12CBCerebellum45.93
55.34
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00429245 22 48 69 DPYFPAGPDALGYDQLGPDSEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018