AutismKB 2.0

Annotation Detail for DIRAS1


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Basic Information Top
Gene Symbol:DIRAS1 ( Di-Ras1,FLJ42681,GBTS1,RIG )
Gene Full Name: DIRAS family, GTP-binding RAS-like 1
Band: 19p13.3
Quick LinksEntrez ID:148252; OMIM: 607862; Uniprot ID:DIRA1_HUMAN; ENSEMBL ID: ENSG00000176490; HGNC ID: 19127
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus15 / 56401226
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult37 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor2 / 2638457
glioma9 / 10688384
head and neck tumor4 / 13630229
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor3 / 9635931
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal73 / 336030721
ovarian tumor0 / 766820 
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor1 / 1249498
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain49 / 110098944
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye16 / 21105475
heart4 / 8962644
intestine2 / 2344728
kidney1 / 2117774
larynx0 / 241450 
liver3 / 20774314
lung4 / 33697411
lymph1 / 4427022
lymph node0 / 916100 
mammary gland3 / 15327119
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas7 / 21481232
parathyroid1 / 2053948
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis2 / 3304426
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9688_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.33 ± 0.72
Basal Forebrain4.11 ± 0.38
Basal Part of Pons4.35 ± 0.66
Cerebellar Cortex4.1 ± 0.62
Cerebellar Nuclei4.04 ± 0.44
Claustrum4.88 ± 0.79
Epithalamus3.58 ± 0.97
Frontal Lobe4.1 ± 0.62
Globus Pallidus4.18 ± 0.57
Hypothalamus3.42 ± 0.73
Insula4.01 ± 0.61
Limbic Lobe4.36 ± 0.64
Mesencephalon3.99 ± 0.69
Myelencephalon4.12 ± 0.78
Occipital Lobe4.37 ± 0.71
Parietal Lobe4.29 ± 0.61
Pontine Tegmentum4.14 ± 0.67
Striatum3.88 ± 0.79
Subthalamus4.08 ± 0.94
Temporal Lobe4.07 ± 0.6
Thalamus4.3 ± 0.6
White Matter2.56 ± 0.63
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Diras1CBCerebellum88.34
100
Diras1CTXCerebral cortex71.35
69.59
Diras1HIPHippocampal region51.04
78.41
Diras1HPFHippocampal formation62.57
78.33
Diras1HYHypothalamus37.18
38.13
Diras1LSXLateral septal complex34.78
29.31
Diras1MBMidbrain69.55
83.42
Diras1MYMedulla67.92
99.04
Diras1OLFOlfactory bulb69.97
70.88
Diras1PPons64.64
91.33
Diras1PALPallidum57.29
75.44
Diras1RHPRetrohippocampal region76.46
77.27
Diras1sAMYStriatum-like amygdalar nuclei51.49
47.81
Diras1STRStriatum46.51
42.32
Diras1STRdStriatum dorsal region42.6
39.08
Diras1STRvStriatum ventral region61
53.01
Diras1THThalamus69.99
80.75
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018