AutismKB 2.0

Annotation Detail for SAMD11


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Basic Information Top
Gene Symbol:SAMD11 ( MGC45873 )
Gene Full Name: sterile alpha motif domain containing 11
Band: 1p36.33
Quick LinksEntrez ID:148398; OMIM: NA; Uniprot ID:SAM11_HUMAN; ENSEMBL ID: ENSG00000187634; HGNC ID: 28706
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus6 / 56401210
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult21 / 193912110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor2 / 3436658
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor1 / 2638453
glioma2 / 10688318
head and neck tumor8 / 13630258
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal40 / 336030711
ovarian tumor0 / 766820 
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer0 / 1026800 
retinoblastoma8 / 46356172
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain6 / 11009895
cervix2 / 4817141
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye16 / 21105475
heart0 / 896260 
intestine1 / 2344724
kidney4 / 21177718
larynx0 / 241450 
liver1 / 2077434
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland8 / 20155396
skin2 / 2105749
spleen0 / 539520 
stomach1 / 9661910
testis0 / 3304420 
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P402510
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.22 ± 0.87
Basal Forebrain5.65 ± 0.68
Basal Part of Pons2.75 ± 0.43
Cerebellar Cortex3.68 ± 0.58
Cerebellar Nuclei4.4 ± 0.73
Claustrum4.33 ± 0.81
Epithalamus5.48 ± 0.67
Frontal Lobe4.11 ± 1.01
Globus Pallidus6.21 ± 0.76
Hypothalamus5.64 ± 0.53
Insula4.18 ± 0.72
Limbic Lobe3.89 ± 1.02
Mesencephalon4.54 ± 0.95
Myelencephalon4.55 ± 0.92
Occipital Lobe4.3 ± 1.02
Parietal Lobe4.17 ± 0.89
Pontine Tegmentum4.8 ± 0.75
Striatum5.37 ± 0.8
Subthalamus3.72 ± 0.72
Temporal Lobe4.12 ± 0.89
Thalamus4.71 ± 0.93
White Matter6.5 ± 0.75
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Samd11CBCerebellum0.55
0.85
Samd11CTXCerebral cortex0.86
1.24
Samd11HIPHippocampal region0.12
0.13
Samd11HPFHippocampal formation0.2
0.32
Samd11HYHypothalamus0.41
0.37
Samd11LSXLateral septal complex0.19
0.36
Samd11MBMidbrain2.74
4.64
Samd11MYMedulla0.51
0.65
Samd11OLFOlfactory bulb0.64
1.34
Samd11PPons2.07
2.95
Samd11PALPallidum0.14
0.15
Samd11RHPRetrohippocampal region0.34
0.59
Samd11sAMYStriatum-like amygdalar nuclei0.6
0.38
Samd11STRStriatum0.14
0.13
Samd11STRdStriatum dorsal region0.06
0.08
Samd11STRvStriatum ventral region0.22
0.18
Samd11THThalamus0.55
0.53
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018