AutismKB 2.0

Annotation Detail for TMEM56


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Basic Information Top
Gene Symbol:TMEM56 ( FLJ31842,MGC102912 )
Gene Full Name: transmembrane protein 56
Band: 1p21.3
Quick LinksEntrez ID:148534; OMIM: NA; Uniprot ID:TMM56_HUMAN; ENSEMBL ID: ENSG00000152078; HGNC ID: 26477
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult57 / 193912129
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal68 / 336030720
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder4 / 29757134
blood3 / 12347824
bone2 / 7165527
bone marrow0 / 488010 
brain20 / 110098918
cervix6 / 48171124
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye16 / 21105475
heart2 / 8962622
intestine2 / 2344728
kidney1 / 2117774
larynx0 / 241450 
liver12 / 20774357
lung4 / 33697411
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta0 / 2808250 
prostate1 / 1893455
salivary gland1 / 2015549
skin8 / 21057437
spleen0 / 539520 
stomach0 / 966190 
testis5 / 33044215
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P19539
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.17 ± 1.08
Basal Forebrain1.75 ± 0.35
Basal Part of Pons1.4 ± 0.36
Cerebellar Cortex1.98 ± 0.6
Cerebellar Nuclei2.01 ± 0.7
Claustrum2.56 ± 0.75
Epithalamus1.39 ± 0.76
Frontal Lobe1.71 ± 0.69
Globus Pallidus1.75 ± 0.79
Hypothalamus1.78 ± 0.72
Insula1.51 ± 0.61
Limbic Lobe1.75 ± 0.66
Mesencephalon1.92 ± 0.78
Myelencephalon1.8 ± 0.69
Occipital Lobe1.77 ± 0.73
Parietal Lobe1.88 ± 0.75
Pontine Tegmentum1.76 ± 0.63
Striatum1.33 ± 0.62
Subthalamus1.87 ± 0.7
Temporal Lobe1.61 ± 0.71
Thalamus1.67 ± 0.62
White Matter2.02 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tmem56CBCerebellum1.97
3.35
Tmem56CTXCerebral cortex9.42
7.32
Tmem56HIPHippocampal region7.78
7.48
Tmem56HPFHippocampal formation7.15
6.44
Tmem56HYHypothalamus2.25
2.71
Tmem56LSXLateral septal complex0.73
1.92
Tmem56MBMidbrain2.32
3.07
Tmem56MYMedulla1.61
3.15
Tmem56OLFOlfactory bulb6.13
6.85
Tmem56PPons4.04
8.17
Tmem56PALPallidum1.94
1.86
Tmem56RHPRetrohippocampal region4.87
3.55
Tmem56sAMYStriatum-like amygdalar nuclei4.27
3.45
Tmem56STRStriatum2.87
2.31
Tmem56STRdStriatum dorsal region1.41
1.08
Tmem56STRvStriatum ventral region7.26
5.18
Tmem56THThalamus31.22
31.99
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018