AutismKB 2.0

Annotation Detail for CTBP1


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Basic Information Top
Gene Symbol:CTBP1 ( BARS,MGC104684 )
Gene Full Name: C-terminal binding protein 1
Band: 4p16.3
Quick LinksEntrez ID:1487; OMIM: 602618; Uniprot ID:CTBP1_HUMAN; ENSEMBL ID: ENSG00000159692; HGNC ID: 2494
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst12 / 62319192
fetus42 / 56401274
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult143 / 193912173
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor13 / 94178138
cervical tumor3 / 3436687
chondrosarcoma14 / 82823169
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor10 / 26384537
glioma13 / 106883121
head and neck tumor4 / 13630229
kidney tumor3 / 6895943
leukemia8 / 9584283
liver tumor10 / 96359103
lung tumor16 / 103127155
lymphoma7 / 7175597
non-neoplasia4 / 9725041
normal232 / 336030769
ovarian tumor6 / 7668278
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS11 / 12568087
prostate cancer7 / 10268068
retinoblastoma4 / 4635686
skin tumor16 / 124949128
soft tissue/muscle tissue tumor11 / 12519187
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland2 / 3319760
ascites1 / 4001524
bladder0 / 297570 
blood9 / 12347872
bone5 / 7165569
bone marrow1 / 4880120
brain91 / 110098982
cervix3 / 4817162
connective tissue14 / 14925593
ear3 / 16212185
embryonic tissue28 / 215722129
esophagus0 / 202090 
eye20 / 21105494
heart6 / 8962666
intestine23 / 23447298
kidney10 / 21177747
larynx0 / 241450 
liver14 / 20774367
lung28 / 33697483
lymph4 / 4427090
lymph node18 / 91610196
mammary gland15 / 15327197
mouth0 / 670520 
muscle6 / 10771555
nerve1 / 1576863
ovary12 / 102051117
pancreas19 / 21481288
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta22 / 28082578
prostate12 / 18934563
salivary gland2 / 2015599
skin21 / 21057499
spleen3 / 5395255
stomach9 / 9661993
testis11 / 33044233
thymus1 / 8113112
thyroid2 / 4747342
tonsil2 / 16999117
trachea1 / 5241319
umbilical cord0 / 136800 
uterus12 / 23287851
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203392_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts524.5
Adipocyte49.65
AdrenalCortex44.35
Adrenalgland122.75
Amygdala548.8
Appendix25.35
AtrioventricularNode7.1
BDCA4+_DentriticCells250.4
Bonemarrow83.7
BronchialEpithelialCells171.6
CD105+_Endothelial145.35
CD14+_Monocytes285.35
CD19+_BCells(neg._sel.)443.3
CD33+_Myeloid233.3
CD34+439.25
CD4+_Tcells456.5
CD56+_NKCells701.25
CD71+_EarlyErythroid199.35
CD8+_Tcells415.2
CardiacMyocytes51.05
Caudatenucleus117.85
Cerebellum351.65
CerebellumPeduncles212.65
CiliaryGanglion8.3
CingulateCortex60.15
Colorectaladenocarcinoma111.4
DorsalRootGanglion26.55
FetalThyroid39.65
Fetalbrain132.5
Fetalliver49.15
Fetallung121.25
GlobusPallidus41.6
Heart170.15
Hypothalamus122.55
Kidney111.7
Leukemia_chronicMyelogenousK-56220.5
Leukemia_promyelocytic-HL-60139.05
Leukemialymphoblastic(MOLT-4)370.45
Liver361.3
Lung820.7
Lymphnode123.65
Lymphoma_burkitts(Daudi)161.8
Lymphoma_burkitts(Raji)589.1
MedullaOblongata136.5
OccipitalLobe64.15
OlfactoryBulb38.1
Ovary22
Pancreas32.15
PancreaticIslet83.85
ParietalLobe29.45
Pituitary81.9
Placenta182.05
Pons51.9
PrefrontalCortex429.6
Prostate717.35
Salivarygland73.45
SkeletalMuscle22.95
Skin11.4
SmoothMuscle16.5
Spinalcord110.7
SubthalamicNucleus77.85
SuperiorCervicalGanglion23.65
TemporalLobe150
Testis52.2
TestisGermCell55.25
TestisIntersitial40.85
TestisLeydigCell30.7
TestisSeminiferousTubule21.4
Thalamus120.05
Thymus313.35
Thyroid453.35
Tongue22.35
Tonsil78.65
Trachea97.85
TrigeminalGanglion8
Uterus235.75
UterusCorpus31.85
WholeBlood383.5
Wholebrain710.65
colon217.9
pineal_day514.06
pineal_night591.02
retina429.925
small_intestine265.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P208992
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.21 ± 0.27
Basal Forebrain6.08 ± 0.25
Basal Part of Pons6.24 ± 0.18
Cerebellar Cortex6.2 ± 0.27
Cerebellar Nuclei6.2 ± 0.42
Claustrum6.35 ± 0.44
Epithalamus5.78 ± 0.18
Frontal Lobe6.11 ± 0.3
Globus Pallidus6.03 ± 0.26
Hypothalamus6.03 ± 0.22
Insula6.07 ± 0.22
Limbic Lobe6.18 ± 0.3
Mesencephalon6.06 ± 0.34
Myelencephalon6.15 ± 0.37
Occipital Lobe6.05 ± 0.36
Parietal Lobe6.13 ± 0.31
Pontine Tegmentum6.08 ± 0.31
Striatum6.27 ± 0.33
Subthalamus6.07 ± 0.27
Temporal Lobe6.13 ± 0.29
Thalamus6.25 ± 0.25
White Matter5.75 ± 0.21
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ctbp1CBCerebellum74.56
100
Ctbp1CTXCerebral cortex100
100
Ctbp1HIPHippocampal region100
100
Ctbp1HPFHippocampal formation100
100
Ctbp1HYHypothalamus100
100
Ctbp1LSXLateral septal complex100
100
Ctbp1MBMidbrain100
100
Ctbp1MYMedulla100
100
Ctbp1OLFOlfactory bulb100
100
Ctbp1PPons83
100
Ctbp1PALPallidum100
100
Ctbp1RHPRetrohippocampal region100
100
Ctbp1sAMYStriatum-like amygdalar nuclei100
100
Ctbp1STRStriatum100
100
Ctbp1STRdStriatum dorsal region100
100
Ctbp1STRvStriatum ventral region100
100
Ctbp1THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CTBP1_HUMAN_20 8 20 27 MNGPLHPR PRIDE
CTBP1_HUMAN_257 10 257 266 QGAFLVNTAR PRIDE
CTBP1_HUMAN_28 9 28 36 PLVALLDGR PRIDE
PAp00000314 19 195 213 AFGFNVLFYDPYLSDGVER Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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