AutismKB 2.0

Annotation Detail for CTBP2


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Basic Information Top
Gene Symbol:CTBP2 ( - )
Gene Full Name: C-terminal binding protein 2
Band: 10q26.13
Quick LinksEntrez ID:1488; OMIM: 602619; Uniprot ID:CTBP2_HUMAN; ENSEMBL ID: ENSG00000175029; HGNC ID: 2495
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst10 / 62319160
fetus42 / 56401274
neonate1 / 3109732
infant2 / 2362084
juvenile1 / 5555617
adult166 / 193912185
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor14 / 94178148
cervical tumor3 / 3436687
chondrosarcoma8 / 8282396
colorectal tumor21 / 114246183
esophageal tumor1 / 1729057
gastrointestinal tumor5 / 11936941
germ cell tumor16 / 26384560
glioma1 / 1068839
head and neck tumor7 / 13630251
kidney tumor8 / 68959116
leukemia1 / 9584210
liver tumor4 / 9635941
lung tumor9 / 10312787
lymphoma1 / 7175513
non-neoplasia7 / 9725071
normal227 / 336030767
ovarian tumor10 / 76682130
pancreatic tumor25 / 104616238
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer16 / 102680155
retinoblastoma8 / 46356172
skin tumor8 / 12494964
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor13 / 90257144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland3 / 3319790
ascites2 / 4001549
bladder1 / 2975733
blood1 / 1234788
bone13 / 71655181
bone marrow8 / 48801163
brain38 / 110098934
cervix3 / 4817162
connective tissue4 / 14925526
ear1 / 1621261
embryonic tissue27 / 215722125
esophagus1 / 2020949
eye26 / 211054123
heart4 / 8962644
intestine36 / 234472153
kidney20 / 21177794
larynx2 / 2414582
liver7 / 20774333
lung44 / 336974130
lymph0 / 442700 
lymph node1 / 9161010
mammary gland18 / 153271117
mouth3 / 6705244
muscle3 / 10771527
nerve3 / 15768190
ovary11 / 102051107
pancreas27 / 214812125
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta23 / 28082581
prostate28 / 189345147
salivary gland0 / 201550 
skin20 / 21057494
spleen2 / 5395237
stomach4 / 9661941
testis17 / 33044251
thymus0 / 811310 
thyroid3 / 4747363
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord1 / 1368073
uterus28 / 232878120
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201219_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.65
Adipocyte6.7
AdrenalCortex8.7
Adrenalgland6.15
Amygdala6.75
Appendix8.15
AtrioventricularNode6.25
BDCA4+_DentriticCells10.7
Bonemarrow7.1
BronchialEpithelialCells14.4
CD105+_Endothelial18.3
CD14+_Monocytes14.95
CD19+_BCells(neg._sel.)7.35
CD33+_Myeloid23.6
CD34+39.9
CD4+_Tcells7.5
CD56+_NKCells100.45
CD71+_EarlyErythroid6.65
CD8+_Tcells6.4
CardiacMyocytes9.3
Caudatenucleus6.3
Cerebellum5.8
CerebellumPeduncles8.3
CiliaryGanglion5.8
CingulateCortex7.25
Colorectaladenocarcinoma6.95
DorsalRootGanglion5.6
FetalThyroid8.9
Fetalbrain6.9
Fetalliver6.5
Fetallung5.7
GlobusPallidus5.3
Heart9.5
Hypothalamus7.35
Kidney5.95
Leukemia_chronicMyelogenousK-5626.05
Leukemia_promyelocytic-HL-605.8
Leukemialymphoblastic(MOLT-4)4.95
Liver9.65
Lung7.65
Lymphnode6.05
Lymphoma_burkitts(Daudi)9.05
Lymphoma_burkitts(Raji)10.15
MedullaOblongata6.45
OccipitalLobe5.9
OlfactoryBulb5.6
Ovary5
Pancreas5.8
PancreaticIslet7.6
ParietalLobe7.7
Pituitary8.25
Placenta6.9
Pons6.8
PrefrontalCortex8.8
Prostate9.25
Salivarygland5.8
SkeletalMuscle9.75
Skin5.95
SmoothMuscle8.6
Spinalcord7.7
SubthalamicNucleus6.45
SuperiorCervicalGanglion9.55
TemporalLobe6.5
Testis5.9
TestisGermCell5.8
TestisIntersitial5.9
TestisLeydigCell7.1
TestisSeminiferousTubule6.1
Thalamus7
Thymus4.65
Thyroid8.85
Tongue7.95
Tonsil6.9
Trachea5.95
TrigeminalGanglion8.3
Uterus5.95
UterusCorpus6.9
WholeBlood8.3
Wholebrain5.35
colon25.2
pineal_day51.2
pineal_night37.74
retina13
small_intestine10.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P103922
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.69 ± 0.45
Basal Forebrain6.7 ± 0.38
Basal Part of Pons6.36 ± 0.25
Cerebellar Cortex6.88 ± 0.28
Cerebellar Nuclei6.57 ± 0.28
Claustrum6.7 ± 0.5
Epithalamus6.63 ± 0.4
Frontal Lobe6.57 ± 0.32
Globus Pallidus6.96 ± 0.32
Hypothalamus6.6 ± 0.27
Insula6.51 ± 0.23
Limbic Lobe6.74 ± 0.34
Mesencephalon6.62 ± 0.37
Myelencephalon6.64 ± 0.35
Occipital Lobe6.58 ± 0.33
Parietal Lobe6.47 ± 0.34
Pontine Tegmentum6.59 ± 0.29
Striatum6.29 ± 0.3
Subthalamus6.21 ± 0.39
Temporal Lobe6.65 ± 0.34
Thalamus6.53 ± 0.3
White Matter6.76 ± 0.36
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ctbp2CBCerebellum41.32
59.59
Ctbp2CTXCerebral cortex26.1
19.85
Ctbp2HIPHippocampal region36.01
53.88
Ctbp2HPFHippocampal formation37.09
43.89
Ctbp2HYHypothalamus31.13
25.49
Ctbp2LSXLateral septal complex30.22
23.88
Ctbp2MBMidbrain25.7
24.12
Ctbp2MYMedulla34.78
38.59
Ctbp2OLFOlfactory bulb38.01
41.43
Ctbp2PPons31.56
32.62
Ctbp2PALPallidum18.57
17.02
Ctbp2RHPRetrohippocampal region37.21
31.55
Ctbp2sAMYStriatum-like amygdalar nuclei17.94
13.95
Ctbp2STRStriatum11.74
8.67
Ctbp2STRdStriatum dorsal region9.17
6.55
Ctbp2STRvStriatum ventral region10.15
7.24
Ctbp2THThalamus16.13
14.41
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CTBP2_HUMAN_34 9 34 42 PLVALLDGR PRIDE
PAp00009826 19 593 611 DLATVAFCDAQSTQEIHEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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