AutismKB 2.0

Annotation Detail for CTGF


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Basic Information Top
Gene Symbol:CTGF ( CCN2,HCS24,IGFBP8,MGC102839,NOV2 )
Gene Full Name: connective tissue growth factor
Band: 6q23.2
Quick LinksEntrez ID:1490; OMIM: 121009; Uniprot ID:CTGF_HUMAN; ENSEMBL ID: ENSG00000118523; HGNC ID: 2500
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body34 / 70761480
blastocyst3 / 6231948
fetus69 / 564012122
neonate17 / 31097546
infant2 / 2362084
juvenile10 / 55556179
adult600 / 1939121309
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma5 / 17475286
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma118 / 828231424
colorectal tumor7 / 11424661
esophageal tumor1 / 1729057
gastrointestinal tumor72 / 119369603
germ cell tumor132 / 263845500
glioma9 / 10688384
head and neck tumor33 / 136302242
kidney tumor11 / 68959159
leukemia5 / 9584252
liver tumor13 / 96359134
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia144 / 972501480
normal1072 / 3360307319
ovarian tumor18 / 76682234
pancreatic tumor36 / 104616344
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor10 / 12494980
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor31 / 90257343
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue6 / 13106457
adrenal gland2 / 3319760
ascites3 / 4001574
bladder2 / 2975767
blood1 / 1234788
bone93 / 716551297
bone marrow40 / 48801819
brain111 / 1100989100
cervix1 / 4817120
connective tissue265 / 1492551775
ear21 / 162121295
embryonic tissue54 / 215722250
esophagus1 / 2020949
eye60 / 211054284
heart3 / 8962633
intestine63 / 234472268
kidney107 / 211777505
larynx5 / 24145207
liver20 / 20774396
lung64 / 336974189
lymph0 / 442700 
lymph node3 / 9161032
mammary gland9 / 15327158
mouth37 / 67052551
muscle2 / 10771518
nerve7 / 15768443
ovary16 / 102051156
pancreas50 / 214812232
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta22 / 28082578
prostate26 / 189345137
salivary gland0 / 201550 
skin91 / 210574432
spleen37 / 53952685
stomach48 / 96619496
testis35 / 330442105
thymus8 / 8113198
thyroid30 / 47473631
tonsil0 / 169990 
trachea44 / 52413839
umbilical cord16 / 136801169
uterus89 / 232878382
vascular200 / 517803862
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209101_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.35
Adipocyte314.8
AdrenalCortex15.25
Adrenalgland92
Amygdala42.55
Appendix91.25
AtrioventricularNode384.75
BDCA4+_DentriticCells9.75
Bonemarrow11.05
BronchialEpithelialCells22.55
CD105+_Endothelial37.2
CD14+_Monocytes10.3
CD19+_BCells(neg._sel.)9.75
CD33+_Myeloid11.9
CD34+16.05
CD4+_Tcells10
CD56+_NKCells10.5
CD71+_EarlyErythroid8.8
CD8+_Tcells9.15
CardiacMyocytes3795.9
Caudatenucleus11.8
Cerebellum8.45
CerebellumPeduncles12.4
CiliaryGanglion359.55
CingulateCortex12.1
Colorectaladenocarcinoma10.35
DorsalRootGanglion192.8
FetalThyroid54.85
Fetalbrain13.55
Fetalliver10.2
Fetallung319.35
GlobusPallidus8.65
Heart25.9
Hypothalamus12.4
Kidney132.35
Leukemia_chronicMyelogenousK-5628.55
Leukemia_promyelocytic-HL-608.35
Leukemialymphoblastic(MOLT-4)7.3
Liver13.55
Lung884.9
Lymphnode70.45
Lymphoma_burkitts(Daudi)13.15
Lymphoma_burkitts(Raji)13.1
MedullaOblongata9.5
OccipitalLobe13.4
OlfactoryBulb206.05
Ovary10.25
Pancreas55.65
PancreaticIslet85.75
ParietalLobe11.65
Pituitary61.5
Placenta541.6
Pons12.6
PrefrontalCortex19.9
Prostate114.15
Salivarygland72.7
SkeletalMuscle10.25
Skin179.05
SmoothMuscle2930.6
Spinalcord15.75
SubthalamicNucleus9.95
SuperiorCervicalGanglion115.6
TemporalLobe9.3
Testis19.9
TestisGermCell73.75
TestisIntersitial56.4
TestisLeydigCell29.15
TestisSeminiferousTubule20.2
Thalamus11
Thymus17.95
Thyroid682.6
Tongue15
Tonsil10.35
Trachea936.45
TrigeminalGanglion134.8
Uterus722.55
UterusCorpus283.95
WholeBlood10.1
Wholebrain17.15
colon105.4
pineal_day12.2
pineal_night12.18
retina362.075
small_intestine438.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P85433
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.16 ± 0.96
Basal Forebrain1.42 ± 0.24
Basal Part of Pons1.46 ± 0.46
Cerebellar Cortex1.48 ± 0.64
Cerebellar Nuclei1.89 ± 0.71
Claustrum2.27 ± 0.86
Epithalamus1.7 ± 0.84
Frontal Lobe1.56 ± 0.73
Globus Pallidus2.12 ± 0.45
Hypothalamus1.46 ± 0.68
Insula1.45 ± 0.82
Limbic Lobe1.95 ± 0.64
Mesencephalon1.81 ± 0.76
Myelencephalon1.73 ± 0.72
Occipital Lobe1.58 ± 0.61
Parietal Lobe1.72 ± 0.84
Pontine Tegmentum1.72 ± 0.74
Striatum1.74 ± 0.62
Subthalamus1.8 ± 0.67
Temporal Lobe1.69 ± 0.75
Thalamus1.58 ± 0.72
White Matter1.97 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
CtgfCBCerebellum1.82
2.77
CtgfCTXCerebral cortex5.63
11.43
CtgfHIPHippocampal region2.71
6.3
CtgfHPFHippocampal formation6.8
16.02
CtgfHYHypothalamus1.82
2.45
CtgfLSXLateral septal complex4.72
8.14
CtgfMBMidbrain2.03
3.93
CtgfMYMedulla3.4
4.27
CtgfOLFOlfactory bulb14.76
19.92
CtgfPPons4.31
6.74
CtgfPALPallidum0.96
1.18
CtgfRHPRetrohippocampal region13.6
28.89
CtgfsAMYStriatum-like amygdalar nuclei0.87
0.88
CtgfSTRStriatum4.92
11.2
CtgfSTRdStriatum dorsal region6.25
15.59
CtgfSTRvStriatum ventral region1.9
2.9
CtgfTHThalamus1.1
1.14
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00009799 13 99 111 DGAPCIFGGTVYR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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