AutismKB 2.0

Annotation Detail for SHISA4


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Basic Information Top
Gene Symbol:SHISA4 ( C1orf40,FLJ18233,MGC102893,MGC129812,MGC129813,TMEM58 )
Gene Full Name: shisa homolog 4 (Xenopus laevis)
Band: 1q32.1
Quick LinksEntrez ID:149345; OMIM: NA; Uniprot ID:SHSA4_HUMAN; ENSEMBL ID: ENSG00000198892; HGNC ID: 27139
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus12 / 56401221
neonate0 / 310970 
infant2 / 2362084
juvenile0 / 555560 
adult61 / 193912131
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma15 / 106883140
head and neck tumor1 / 1363027
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal103 / 336030730
ovarian tumor1 / 7668213
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain87 / 110098979
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye12 / 21105456
heart1 / 8962611
intestine0 / 2344720 
kidney4 / 21177718
larynx0 / 241450 
liver0 / 2077430 
lung8 / 33697423
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle13 / 107715120
nerve1 / 1576863
ovary1 / 1020519
pancreas7 / 21481232
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland1 / 2015549
skin2 / 2105749
spleen0 / 539520 
stomach1 / 9661910
testis1 / 3304423
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5907_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.41 ± 0.38
Basal Forebrain6.4 ± 0.21
Basal Part of Pons6.69 ± 0.4
Cerebellar Cortex6.07 ± 0.26
Cerebellar Nuclei6.45 ± 0.31
Claustrum5.88 ± 0.62
Epithalamus5.93 ± 0.65
Frontal Lobe6.49 ± 0.43
Globus Pallidus6.9 ± 0.35
Hypothalamus6.22 ± 0.45
Insula6.37 ± 0.29
Limbic Lobe6.22 ± 0.38
Mesencephalon6.33 ± 0.39
Myelencephalon6.43 ± 0.45
Occipital Lobe6.07 ± 0.35
Parietal Lobe6.39 ± 0.38
Pontine Tegmentum6.31 ± 0.34
Striatum6.31 ± 0.3
Subthalamus5.89 ± 0.87
Temporal Lobe6.52 ± 0.39
Thalamus6.64 ± 0.34
White Matter7.12 ± 0.36
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tmem58CBCerebellum1.03
1.28
Tmem58CTXCerebral cortex6.33
6.1
Tmem58HIPHippocampal region3.3
3.68
Tmem58HPFHippocampal formation3.81
3.96
Tmem58HYHypothalamus2.18
2.96
Tmem58LSXLateral septal complex0.54
0.81
Tmem58MBMidbrain0.6
0.8
Tmem58MYMedulla1.74
2.72
Tmem58OLFOlfactory bulb5.04
5.62
Tmem58PPons1.3
2.01
Tmem58PALPallidum0.44
0.43
Tmem58RHPRetrohippocampal region4.79
4.45
Tmem58sAMYStriatum-like amygdalar nuclei0.7
0.92
Tmem58STRStriatum0.66
0.64
Tmem58STRdStriatum dorsal region0.77
0.72
Tmem58STRvStriatum ventral region0.38
0.29
Tmem58THThalamus0.8
0.78
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018