AutismKB 2.0

Annotation Detail for CTNNA2


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Basic Information Top
Gene Symbol:CTNNA2 ( CAP-R,CAPR,CT114,CTNR,DKFZp686H02198 )
Gene Full Name: catenin (cadherin-associated protein), alpha 2
Band: 2p12
Quick LinksEntrez ID:1496; OMIM: 114025; Uniprot ID:CTNA2_HUMAN; ENSEMBL ID: ENSG00000066032; HGNC ID: 2510
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus16 / 56401228
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult50 / 193912125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor14 / 26384553
glioma3 / 10688328
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal175 / 336030752
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain159 / 1100989144
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye13 / 21105461
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle4 / 10771537
nerve1 / 1576863
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis27 / 33044281
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205373_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.55
Adipocyte7.9
AdrenalCortex8.8
Adrenalgland6.85
Amygdala291.3
Appendix10.3
AtrioventricularNode6.7
BDCA4+_DentriticCells7.55
Bonemarrow8.55
BronchialEpithelialCells7.3
CD105+_Endothelial8.05
CD14+_Monocytes8.15
CD19+_BCells(neg._sel.)8.7
CD33+_Myeloid9.65
CD34+9.4
CD4+_Tcells8.55
CD56+_NKCells8.85
CD71+_EarlyErythroid7.8
CD8+_Tcells7.25
CardiacMyocytes11.3
Caudatenucleus38.25
Cerebellum9.3
CerebellumPeduncles10.9
CiliaryGanglion6.85
CingulateCortex123.15
Colorectaladenocarcinoma8
DorsalRootGanglion7.5
FetalThyroid8.3
Fetalbrain207.3
Fetalliver6.9
Fetallung6.15
GlobusPallidus92.75
Heart12.6
Hypothalamus81.3
Kidney6.95
Leukemia_chronicMyelogenousK-5627
Leukemia_promyelocytic-HL-607.35
Leukemialymphoblastic(MOLT-4)6.1
Liver11.35
Lung8.25
Lymphnode6.6
Lymphoma_burkitts(Daudi)10.55
Lymphoma_burkitts(Raji)11.45
MedullaOblongata57.5
OccipitalLobe166.45
OlfactoryBulb6.55
Ovary5.95
Pancreas6.8
PancreaticIslet8.95
ParietalLobe58
Pituitary11.3
Placenta7.9
Pons45.15
PrefrontalCortex435.9
Prostate8.7
Salivarygland6.6
SkeletalMuscle9.9
Skin7.55
SmoothMuscle9.3
Spinalcord15.2
SubthalamicNucleus101.05
SuperiorCervicalGanglion12.55
TemporalLobe71.7
Testis26.85
TestisGermCell30.65
TestisIntersitial19.25
TestisLeydigCell12.5
TestisSeminiferousTubule14.6
Thalamus189.5
Thymus5.7
Thyroid9.05
Tongue8.4
Tonsil7.65
Trachea6.8
TrigeminalGanglion9.55
Uterus6.05
UterusCorpus7.7
WholeBlood8.05
Wholebrain133.2
colon7.5
pineal_day33.6
pineal_night17.7
retina55.825
small_intestine7.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P33477
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.3 ± 0.37
Basal Forebrain7.86 ± 0.17
Basal Part of Pons7.84 ± 0.28
Cerebellar Cortex7.27 ± 0.3
Cerebellar Nuclei7.32 ± 0.5
Claustrum7.61 ± 0.48
Epithalamus7.79 ± 0.62
Frontal Lobe7.89 ± 0.47
Globus Pallidus7.44 ± 0.66
Hypothalamus7.39 ± 0.46
Insula7.99 ± 0.35
Limbic Lobe8.12 ± 0.51
Mesencephalon7.62 ± 0.55
Myelencephalon7.78 ± 0.55
Occipital Lobe8.08 ± 0.46
Parietal Lobe7.96 ± 0.47
Pontine Tegmentum7.88 ± 0.41
Striatum7.45 ± 0.86
Subthalamus6.98 ± 0.13
Temporal Lobe8.14 ± 0.35
Thalamus8.17 ± 0.47
White Matter6.31 ± 0.76
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ctnna2CBCerebellum10.24
15.04
Ctnna2CTXCerebral cortex28.33
26.96
Ctnna2HIPHippocampal region13.6
16.11
Ctnna2HPFHippocampal formation14.82
15.72
Ctnna2HYHypothalamus4.16
4.17
Ctnna2LSXLateral septal complex4.68
4.22
Ctnna2MBMidbrain5.62
6.44
Ctnna2MYMedulla5.32
7.31
Ctnna2OLFOlfactory bulb19.08
16.12
Ctnna2PPons6.63
8.64
Ctnna2PALPallidum12.62
19.32
Ctnna2RHPRetrohippocampal region17.06
15.46
Ctnna2sAMYStriatum-like amygdalar nuclei11.9
11.96
Ctnna2STRStriatum6.82
9.06
Ctnna2STRdStriatum dorsal region5.56
8.33
Ctnna2STRvStriatum ventral region9.04
11.55
Ctnna2THThalamus10.9
10.78
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00010534 9 331 339 IVAECNAVR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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