AutismKB 2.0

Annotation Detail for FAM109B


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Basic Information Top
Gene Symbol:FAM109B ( DKFZp686J07229,MGC125831,MGC125832,Ses2 )
Gene Full Name: family with sequence similarity 109, member B
Band: 22q13.2
Quick LinksEntrez ID:150368; OMIM: NA; Uniprot ID:F109B_HUMAN; ENSEMBL ID: ENSG00000177096; HGNC ID: 27161
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus29 / 56401251
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult37 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor2 / 2638457
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal81 / 336030724
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone4 / 7165555
bone marrow1 / 4880120
brain6 / 11009895
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye5 / 21105423
heart10 / 89626111
intestine1 / 2344724
kidney0 / 2117770 
larynx0 / 241450 
liver1 / 2077434
lung6 / 33697417
lymph0 / 442700 
lymph node3 / 9161032
mammary gland2 / 15327113
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta21 / 28082574
prostate0 / 1893450 
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10576_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala11.36 ± 0.52
Basal Forebrain11.14 ± 0.38
Basal Part of Pons11.27 ± 0.18
Cerebellar Cortex10.86 ± 0.21
Cerebellar Nuclei11.32 ± 0.25
Claustrum11.53 ± 0.42
Epithalamus10.6 ± 0.44
Frontal Lobe11.3 ± 0.4
Globus Pallidus11.45 ± 0.29
Hypothalamus11 ± 0.21
Insula11.19 ± 0.34
Limbic Lobe11.35 ± 0.47
Mesencephalon11.25 ± 0.35
Myelencephalon11.23 ± 0.41
Occipital Lobe11.21 ± 0.4
Parietal Lobe11.25 ± 0.36
Pontine Tegmentum11.15 ± 0.36
Striatum11.42 ± 0.43
Subthalamus11.05 ± 0.12
Temporal Lobe11.21 ± 0.43
Thalamus11.25 ± 0.35
White Matter10.89 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
C920005C14RikCBCerebellum0.56
0.86
C920005C14RikCTXCerebral cortex0.88
1.08
C920005C14RikHIPHippocampal region0.43
0.6
C920005C14RikHPFHippocampal formation0.33
0.54
C920005C14RikHYHypothalamus0.19
0.37
C920005C14RikLSXLateral septal complex0.57
0.61
C920005C14RikMBMidbrain0.25
0.35
C920005C14RikMYMedulla0.4
0.6
C920005C14RikOLFOlfactory bulb0.92
1.02
C920005C14RikPPons0.07
0.1
C920005C14RikPALPallidum0.17
0.13
C920005C14RikRHPRetrohippocampal region0.16
0.34
C920005C14RiksAMYStriatum-like amygdalar nuclei0.17
0.12
C920005C14RikSTRStriatum0.33
0.51
C920005C14RikSTRdStriatum dorsal region0.39
0.69
C920005C14RikSTRvStriatum ventral region0.2
0.16
C920005C14RikTHThalamus2.12
3.03
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018