AutismKB 2.0

Annotation Detail for NFAM1


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Basic Information Top
Gene Symbol:NFAM1 ( CNAIP,FLJ40652,bK126B4.4 )
Gene Full Name: NFAT activating protein with ITAM motif 1
Band: 22q13.2
Quick LinksEntrez ID:150372; OMIM: 608740; Uniprot ID:NFAM1_HUMAN; ENSEMBL ID: ENSG00000235568; HGNC ID: 29872
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult24 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma5 / 10688346
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia13 / 95842135
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal12 / 33603073
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood15 / 123478121
bone2 / 7165527
bone marrow1 / 4880120
brain7 / 11009896
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine6 / 23447225
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen2 / 5395237
stomach0 / 966190 
testis1 / 3304423
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6225_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.27 ± 0.81
Basal Forebrain3.88 ± 0.28
Basal Part of Pons4.03 ± 0.37
Cerebellar Cortex3.55 ± 0.54
Cerebellar Nuclei4.11 ± 0.45
Claustrum4.49 ± 0.75
Epithalamus3 ± 0.22
Frontal Lobe3.86 ± 0.67
Globus Pallidus4.67 ± 0.27
Hypothalamus3.67 ± 0.4
Insula3.71 ± 0.62
Limbic Lobe4.02 ± 0.74
Mesencephalon3.97 ± 0.63
Myelencephalon3.94 ± 0.66
Occipital Lobe3.86 ± 0.74
Parietal Lobe3.96 ± 0.69
Pontine Tegmentum3.74 ± 0.57
Striatum4.12 ± 0.59
Subthalamus3.39 ± 0.6
Temporal Lobe3.87 ± 0.68
Thalamus3.84 ± 0.48
White Matter4.41 ± 0.56
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nfam1CBCerebellum5.42
7.36
Nfam1CTXCerebral cortex2.96
3.37
Nfam1HIPHippocampal region3.66
5.26
Nfam1HPFHippocampal formation3.2
3.87
Nfam1HYHypothalamus0.51
0.51
Nfam1LSXLateral septal complex0.21
0.17
Nfam1MBMidbrain0.82
0.98
Nfam1MYMedulla6.72
8.48
Nfam1OLFOlfactory bulb4.14
3.53
Nfam1PPons2.92
2.87
Nfam1PALPallidum0.6
0.5
Nfam1RHPRetrohippocampal region2.35
1.84
Nfam1sAMYStriatum-like amygdalar nuclei0.26
0.36
Nfam1STRStriatum1.38
2.39
Nfam1STRdStriatum dorsal region1.86
3.56
Nfam1STRvStriatum ventral region0.83
0.6
Nfam1THThalamus1.88
2.88
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018