AutismKB 2.0

Annotation Detail for PROM2


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Basic Information Top
Gene Symbol:PROM2 ( MGC138714,PROML2 )
Gene Full Name: prominin 2
Band: 2q11.1
Quick LinksEntrez ID:150696; OMIM: NA; Uniprot ID:PROM2_HUMAN; ENSEMBL ID: ENSG00000155066; HGNC ID: 20685
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult30 / 193912115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor6 / 11424652
esophageal tumor4 / 17290231
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor14 / 136302102
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal19 / 33603075
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain5 / 11009894
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus4 / 20209197
eye2 / 2110549
heart0 / 896260 
intestine12 / 23447251
kidney4 / 21177718
larynx4 / 24145165
liver0 / 2077430 
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth8 / 67052119
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta2 / 2808257
prostate4 / 18934521
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach2 / 9661920
testis2 / 3304426
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11446_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.95 ± 0.92
Basal Forebrain4.01 ± 0.27
Basal Part of Pons3.23 ± 0.72
Cerebellar Cortex3.42 ± 0.71
Cerebellar Nuclei3.65 ± 0.49
Claustrum4.24 ± 0.8
Epithalamus3.41 ± 0.45
Frontal Lobe3.46 ± 0.76
Globus Pallidus4.08 ± 0.61
Hypothalamus3.27 ± 0.54
Insula2.94 ± 0.98
Limbic Lobe3.54 ± 0.76
Mesencephalon3.73 ± 1.05
Myelencephalon3.6 ± 0.73
Occipital Lobe3.8 ± 0.65
Parietal Lobe3.62 ± 0.65
Pontine Tegmentum3.57 ± 0.72
Striatum3.84 ± 0.74
Subthalamus3.59 ± 0.57
Temporal Lobe3.41 ± 0.78
Thalamus3.55 ± 0.71
White Matter4.65 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Prom2CBCerebellum6.19
6.31
Prom2CTXCerebral cortex9.62
6.47
Prom2HIPHippocampal region6.18
5.99
Prom2HPFHippocampal formation5.71
4.81
Prom2HYHypothalamus3.16
2.25
Prom2LSXLateral septal complex5.74
3.92
Prom2MBMidbrain5.34
4.93
Prom2MYMedulla7.32
7.04
Prom2OLFOlfactory bulb8.12
5.49
Prom2PPons6.09
6.18
Prom2PALPallidum3.52
2.57
Prom2RHPRetrohippocampal region4.67
3.12
Prom2sAMYStriatum-like amygdalar nuclei1.96
1.17
Prom2STRStriatum3.15
1.95
Prom2STRdStriatum dorsal region2.5
1.58
Prom2STRvStriatum ventral region4.37
2.43
Prom2THThalamus10.27
8.52
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018