AutismKB 2.0

Annotation Detail for SEPT10


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SEPT10 ( FLJ11619 )
Gene Full Name: septin 10
Band: 2q13
Quick LinksEntrez ID:151011; OMIM: 611737; Uniprot ID:SEP10_HUMAN; ENSEMBL ID: ENSG00000186522; HGNC ID: 14349
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst4 / 6231964
fetus24 / 56401242
neonate2 / 3109764
infant0 / 236200 
juvenile2 / 5555635
adult81 / 193912141
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor8 / 9417884
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor3 / 11424626
esophageal tumor3 / 17290173
gastrointestinal tumor7 / 11936958
germ cell tumor9 / 26384534
glioma6 / 10688356
head and neck tumor4 / 13630229
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor4 / 9635941
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia4 / 9725041
normal157 / 336030746
ovarian tumor2 / 7668226
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor6 / 12494948
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone3 / 7165541
bone marrow0 / 488010 
brain50 / 110098945
cervix2 / 4817141
connective tissue3 / 14925520
ear1 / 1621261
embryonic tissue12 / 21572255
esophagus4 / 20209197
eye3 / 21105414
heart5 / 8962655
intestine9 / 23447238
kidney18 / 21177784
larynx0 / 241450 
liver9 / 20774343
lung11 / 33697432
lymph0 / 442700 
lymph node1 / 9161010
mammary gland12 / 15327178
mouth4 / 6705259
muscle0 / 1077150 
nerve2 / 15768126
ovary0 / 1020510 
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta19 / 28082567
prostate5 / 18934526
salivary gland1 / 2015549
skin14 / 21057466
spleen2 / 5395237
stomach8 / 9661982
testis48 / 330442145
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus14 / 23287860
vascular10 / 51780193
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212698_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.15
Adipocyte155.45
AdrenalCortex20.25
Adrenalgland11.6
Amygdala55.3
Appendix21.35
AtrioventricularNode17.05
BDCA4+_DentriticCells9
Bonemarrow9.8
BronchialEpithelialCells262.6
CD105+_Endothelial11
CD14+_Monocytes15.45
CD19+_BCells(neg._sel.)13.6
CD33+_Myeloid11.05
CD34+10.6
CD4+_Tcells9
CD56+_NKCells9.95
CD71+_EarlyErythroid8.7
CD8+_Tcells7.95
CardiacMyocytes72.95
Caudatenucleus15.8
Cerebellum7.5
CerebellumPeduncles11.25
CiliaryGanglion23.05
CingulateCortex12.2
Colorectaladenocarcinoma326.55
DorsalRootGanglion45.8
FetalThyroid21
Fetalbrain38.05
Fetalliver43.3
Fetallung191.1
GlobusPallidus7.95
Heart14.45
Hypothalamus66.85
Kidney12.85
Leukemia_chronicMyelogenousK-56236.75
Leukemia_promyelocytic-HL-608.2
Leukemialymphoblastic(MOLT-4)6.9
Liver13.5
Lung22.4
Lymphnode81.95
Lymphoma_burkitts(Daudi)11.9
Lymphoma_burkitts(Raji)13.55
MedullaOblongata16.9
OccipitalLobe40
OlfactoryBulb125.45
Ovary23
Pancreas64.9
PancreaticIslet33.85
ParietalLobe17.2
Pituitary16.05
Placenta104.55
Pons11.1
PrefrontalCortex17.6
Prostate93.75
Salivarygland67.85
SkeletalMuscle13.9
Skin96.55
SmoothMuscle150.55
Spinalcord170.95
SubthalamicNucleus8.75
SuperiorCervicalGanglion17
TemporalLobe8.55
Testis85.6
TestisGermCell174.4
TestisIntersitial217.85
TestisLeydigCell130.45
TestisSeminiferousTubule83.4
Thalamus33.2
Thymus12.85
Thyroid307.1
Tongue74.2
Tonsil18.75
Trachea61.15
TrigeminalGanglion39.85
Uterus292.3
UterusCorpus37.45
WholeBlood9.75
Wholebrain9.75
colon172.1
pineal_day12.44
pineal_night16.02
retina109.25
small_intestine89.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P91168
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.08 ± 0.57
Basal Forebrain6.82 ± 0.34
Basal Part of Pons5.98 ± 0.47
Cerebellar Cortex5.65 ± 0.38
Cerebellar Nuclei7.23 ± 0.58
Claustrum6.08 ± 0.58
Epithalamus7.12 ± 0.37
Frontal Lobe6.15 ± 0.69
Globus Pallidus8.22 ± 0.4
Hypothalamus6.65 ± 0.43
Insula5.76 ± 0.45
Limbic Lobe5.82 ± 0.88
Mesencephalon6.68 ± 0.59
Myelencephalon6.37 ± 0.61
Occipital Lobe6.51 ± 0.52
Parietal Lobe6.17 ± 0.72
Pontine Tegmentum6.52 ± 0.51
Striatum6.95 ± 0.63
Subthalamus7 ± 0.03
Temporal Lobe6.01 ± 0.62
Thalamus6.48 ± 0.43
White Matter8.84 ± 0.58
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sept10CBCerebellum21.99
39.36
Sept10CTXCerebral cortex32.25
19.25
Sept10HIPHippocampal region11.94
10.99
Sept10HPFHippocampal formation13.25
9.96
Sept10HYHypothalamus18.24
10.84
Sept10LSXLateral septal complex11.43
5.8
Sept10MBMidbrain22.7
16.37
Sept10MYMedulla33.33
31.65
Sept10OLFOlfactory bulb23.4
19.11
Sept10PPons33.5
30.03
Sept10PALPallidum23.54
14.42
Sept10RHPRetrohippocampal region15.72
8.4
Sept10sAMYStriatum-like amygdalar nuclei35.94
22.06
Sept10STRStriatum10.02
5.55
Sept10STRdStriatum dorsal region4.74
2.32
Sept10STRvStriatum ventral region15.92
8.27
Sept10THThalamus78.42
77.99
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00001113 27 325 351 CKLEEMGFTDVGPENKPVSVQETYEAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved